Prophylaxis of hereditary angioedema attacks: A randomized trial of oral plasma kallikrein inhibition with avoralstat

Affiliations

• 1 Centre of Pediatrics III, Department of Hematology, Oncology and Hemostasis, Comprehensive Care Centre for Thrombosis and Hemostasis, Johann Wolfgang Goethe University Hospital, Frankfurt am Main, Germany.
• 2 Department of Dermatology and Allergy, Allergie-Centrum-Charité, Charité - Universitätsmedizin Berlin, Berlin, Germany.
• 3 Institute of Clinical Pharmacology, Johann Wolfgang Goethe-University, Frankfurt, Germany.
• 4 Haemophilia Centre Rhine Main, Frankfurt-Mörfelden, Germany.
• 5 Department of Immunology, Barts Health NHS Trust, London, United Kingdom.
• 6 HNO-Klinik, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.
• 7 Pharstat Inc, Durham, NC.
• 8 BioCryst Pharmaceuticals Inc, Durham, NC.
• 9 Department of Dermatology and Allergy, Allergie-Centrum-Charité, Charité - Universitätsmedizin Berlin, Berlin, Germany. Electronic address: Marcus.Maurer@charite.de.