2. Membrane Transporter/Ion Channel
  3. Sodium Channel
  4. Mexiletine hydrochloride (Standard)

Mexiletine hydrochloride (Standard)  (Synonyms: 盐酸美西律 (标准品); ; KOE-1173 hydrochloride (Standard))

目录号: HY-A0093R 纯度: ≥98%
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Mexiletine (hydrochloride) (Standard) 是 Mexiletine (hydrochloride) 的分析标准品。本产品用于研究及分析应用。Mexiletine 是一种口服有效的抗心律失常剂，也被发现对肌强直和神经病理性疼痛有效。Mexiletine 通过阻断钠离子通道 (IC50 : 75±8 μM 于封闭性阻断, 23.6±2.8 μM 于使用依赖性阻断) 发挥作用，可被用于心血管与神经病学研究。

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Mexiletine hydrochloride (Standard) Chemical Structure

Mexiletine hydrochloride (Standard) Chemical Structure

CAS No. : 5370-01-4

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生物活性

Mexiletine (hydrochloride) (Standard) is the analytical standard of Mexiletine (hydrochloride). This product is intended for research and analytical applications. Mexiletine is an orally effective antiarrhythmic agent which has also been found to be effective for myotonia and neuropathic pain. Mexiletine exerts its efficacy through blocking sodium channels (IC50 : 75±8 μM for tonic block, 23.6±2.8 μM for use-dependent block), therefore can be used for cardiovascular and neurological research.

分子量

215.72

Formula

C11H18ClNO
CAS 号
中文名称

盐酸美西律 (标准品)；
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

Mexiletine hydrochloride (Standard) 相关分类

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
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  • Do most proteins show cross-species activity?

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Keywords:

Mexiletine hydrochloride (Standard)5370-01-4KOE-1173 hydrochloride (Standard)盐酸美西律 (标准品)Sodium ChannelNa channelsNa+ channelsantiarrhythmicClass IBmyocardialischemiamyotonianeuropathic painsodium channelcardiovascularneurologicalHEK293AhiPSC-CMsSprague-Dawley ratsInhibitorinhibitorinhibit

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