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  3. Muscle homing peptide M12

Muscle homing peptide M12 能优先结合到肌肉细胞表面的蛋白质。Muscle homing peptide M12 促进了纳米颗粒(NPs) 在肌母细胞中的细胞内摄取。Muscle homing peptide M12 通过 N-羟基琥珀酰亚胺酯反应与 PLGA-PEG 纳米颗粒共价连接,连接位置在肽链的 N-末端 α-氨基基团上。

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Muscle homing peptide M12 Chemical Structure

Muscle homing peptide M12 Chemical Structure

CAS No. : 2896181-32-9

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Muscle homing peptide M12 can preferentially bind to surface protein of muscle cells. Muscle homing peptide M12 mediates enhanced cellular uptake of nanoparticles (NPs) in myoblasts in vitro. Muscle homing peptide M12 is covalently conjugated to PLGA-PEG NPs via the N-terminal α-amino groups of peptides using the N-hydroxysuccinimide ester reaction[1][2].

分子量

1417.58

Formula

C59H100N24O17

CAS 号
Sequence

Arg-Arg-Gln-Pro-Pro-Arg-Ser-Ile-Ser-Ser-His-Pro

Sequence Shortening

RRQPPRSISSHP

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Muscle homing peptide M12 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Muscle homing peptide M12
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HY-P10646
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