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  3. P18IN005 hydrochloride

P18IN005 hydrochloride 是一种 p18 抑制剂,在负向调节造血干细胞 (HSC) 自我更新方面表现出强效活性。研究表明,P18IN005 hydrochloride 在抑制小鼠模型中的 HSC 自我更新方面比 p27 更有效。P18IN005 hydrochloride 促进短期培养中功能性 HSC 的扩增。

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P18IN005 hydrochloride Chemical Structure

P18IN005 hydrochloride Chemical Structure

CAS No. : 7403-44-3

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生物活性

P18IN005 hydrochloride is a novel inhibitor of p18, exhibiting potent activity in negatively regulating haematopoietic stem cell (HSC) self-renewal. P18IN005 hydrochloride has been shown to be more effective than p27 in inhibiting HSC self-renewal in mouse models. P18IN005 hydrochloride promotes the expansion of functional HSCs in short-term cultures. P18IN005 hydrochloride serves as a valuable tool for dissecting the signaling pathways involved in stem cell self-renewal.

分子量

333.85

Formula

C19H24ClNO2

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

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参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
P18IN005 hydrochloride
目录号:
HY-115893A
需求量: