2. Stem Cell/Wnt TGF-beta/Smad
  3. PKA
  4. PKI(5-22)amide

PKI(5-22)amide 是环 AMP 依赖性蛋白激酶 (PKA) 抑制剂的活性片段。PKI(5-22)amide 抑制 PKA 激活，但不能减弱 CRF1 受体的同源脱敏作用。

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PKI(5-22)amide Chemical Structure

PKI(5-22)amide Chemical Structure

CAS No. : 100853-58-5

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PKI(5-22)amide 相关抗体

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PKA PKAR

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

PKI(5-22)amide is the active inhibitory fragment of the inhibitor of the cyclic AMP-dependent protein kinase (PKA). PKI(5-22)amide inhibits PKA activation, but fails to attenuate homologous desensitization of CRF1 receptors[1][2].

体外研究
(In Vitro)

PKI(5-22)amide (1 μM; 1 min) fails to block CRF1 receptor (100 nM; 30 min) desensitization in Y-79 cells permeabilized with Streptolysin O (HY-135416)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

PKI(5-22)amide 相关抗体:
分子量

1969.17

Formula

C84H137N29O26
CAS 号
Sequence Shortening

TTYADFIASGRTGRRNAI-NH2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

PKI(5-22)amide 相关分类

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  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PKI(5-22)amide100853-58-5PKAProtein kinase Ahomologous desensitizationactive inhibitory fragmentCRF1 receptorsInhibitorinhibitorinhibit

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