2. GPCR/G Protein Neuronal Signaling
  3. GPR119
  4. PSN 375963 hydrochloride

PSN 375963 hydrochloride 是一种有效的 GPR119 激动剂，对人和小鼠的 EC50 分别为 8.4 和 7.9 μM。PSN 375963 hydrochloride 显示出与内源性油酰乙醇酰胺 (OEA) 相似的效力。

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PSN 375963 hydrochloride Chemical Structure

PSN 375963 hydrochloride Chemical Structure

CAS No. : 1781834-82-9

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PSN 375963 hydrochloride 的其他形式现货产品:

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PSN 375963 hydrochloride 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

PSN 375963 hydrochloride is a potent GPR119 agonist, with EC50s of 8.4 and 7.9 μM for human and mouse GPR119, respectively. PSN 375963 hydrochloride shows similar potency to the endogenous agonist oleoylethanolamide (OEA)[1][2].

体外研究
(In Vitro)

The endogenous ligand OEA signals through GPR119 in a manner similar to glucagon-like peptide-1 (GLP-1) and its receptor with respect to insulin secretion, intracellular calcium and cAMP[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

PSN 375963 hydrochloride 相关抗体:
分子量

321.84

Formula

C17H24ClN3O
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

PSN 375963 hydrochloride 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PSN 3759631781834-82-9PSN375963PSN-375963GPR119G Protein-Coupled Receptor 119endogenouscAMPligandorphanreceptorInhibitorinhibitorinhibit

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产品名称：
PSN 375963 hydrochloride
目录号：
HY-108258A
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