2. GPCR/G Protein Neuronal Signaling Membrane Transporter/Ion Channel
  3. Cannabinoid Receptor TRP Channel
  4. (R)-Methanandamide

(R)-Methanandamide  (Synonyms: AM-356)

目录号: HY-101389
产品使用指南

摩尔计算器

(R)-Methanandamide (AM-356)，内源性大麻素配体 Anandamide 的类似物，是一种有效的 CB1 激动剂，Ki 为 20 nM。(R)-Methanandamide 也能激活 TRPV1 受体。

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(R)-Methanandamide Chemical Structure

(R)-Methanandamide Chemical Structure

CAS No. : 157182-49-5

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规格 价格 是否有货
5 mg ￥880
询问价格 & 货期
10 mg ￥1700
询问价格 & 货期
25 mg ￥3400
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Customer Review

(R)-Methanandamide 相关抗体

Top Publications Citing Use of Products

查看 Cannabinoid Receptor 亚型特异性产品:

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CB1 CB2

查看 TRP Channel 亚型特异性产品:

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TRPC TRPM TRPV TRPA TRPML

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

(R)-Methanandamide (AM-356), an analog of the endocannabinoid ligand Anandamide, is a potent CB1 agonist with a Ki of 20 nM. (R)-Methanandamide also activates vanilloid (TRPV1) receptors[1][2].

IC50 & Target[1][2]

CB1

20 nM (Ki)

TRPV1

 

体外研究
(In Vitro)

The endogenous cannabinoid (R)-Methanandamide exerts differential anti- and pronociceptive effects by activating both cannabinoid (CB1) and vanilloid (TRPV1) receptors of nociceptive primary afferents[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

(R)-Methanandamide 相关抗体:
分子量

361.56

Formula

C23H39NO2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

(R)-Methanandamide 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(R)-Methanandamide157182-49-5AM-356AM356AM 356Cannabinoid ReceptorTRP ChannelTransient receptor potential channelsCB1endocannabinoidAnandamidevanilloidTRPV1Inhibitorinhibitorinhibit

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