2. GPCR/G Protein Neuronal Signaling
  3. 5-HT Receptor
  4. R(+)-8-OH-DPAT hydrobromide

R(+)-8-OH-DPAT hydrobromide  (Synonyms: (R)-8-Hydroxy-2-dipropylaminotetralin hydrobromide)

目录号: HY-101377A
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摩尔计算器

R(+)-8-OH-DPAT ((R)-8-Hydroxy-2-dipropylaminotetralin) hydrobromide 是一种有效的 5-HT1A 激动剂。R(+)-8-OH-DPAT hydrobromide 可增强 SUL (HY-B1059) 诱导的内侧前额叶皮质 (mPFC) 中的多巴胺 (DA) 释放。

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R(+)-8-OH-DPAT hydrobromide Chemical Structure

R(+)-8-OH-DPAT hydrobromide Chemical Structure

CAS No. : 78095-19-9

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Other Forms of R(+)-8-OH-DPAT hydrobromide:

R(+)-8-OH-DPAT hydrobromide 相关抗体

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  • 生物活性

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生物活性

R(+)-8-OH-DPAT ((R)-8-Hydroxy-2-dipropylaminotetralin) hydrobromide is a potent 5-HT1A agonist. R(+)-8-OH-DPAT potentiates SUL (HY-B1059)-induced dopamine (DA) release in the medial prefrontal cortex (mPFC)[1].

IC50 & Target[1]

5-HT1A Receptor

 

体内研究
(In Vivo)

R(+)-8-OH-DPAT hydrobromide (0.05 mg/kg; s.c.) 增强 SUL (HY-B1059) (10 和 25 mg/kg) 诱导的内侧前额叶皮质 (Mpfc) 多巴胺 (DA) 释放[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 250-350 g, Male Sprague-Dawley albino rats[1]
Dosage: 0.05 mg/kg
Administration: S.c.; 30 min before SUL
Result: Potentiated SUL (HY-B1059) (10 and 25 mg/kg)-induced dopamine (DA) release in the medial prefrontal cortex (mPFC).
分子量

328.29

Formula

C16H26BrNO
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

R(+)-8-OH-DPAT hydrobromide 相关分类

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Keywords:

R(+)-8-OH-DPAT78095-19-9(R)-8-Hydroxy-2-dipropylaminotetralin5-HT ReceptorSerotonin Receptor5-hydroxytryptamine ReceptormPFCdopamineSULInhibitorinhibitorinhibit

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