2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. nAChR
  4. R-(+)-Cotinine

R-(+)-Cotinine  (Synonyms: R-(+)-可替宁; (+)-Cotinine; (R)-Cotinine; (R)-NIH-10498)

目录号: HY-B1178A
产品使用指南

摩尔计算器

R-(+)-Cotinine ((+)-Cotinine) 是一种尼古丁代谢物，在广泛的药理靶标中缺乏显着活性。R-(+)-Cotinine 可以增强人 α7 nAChR 中的 Ach 诱发电流。

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R-(+)-Cotinine Chemical Structure

R-(+)-Cotinine Chemical Structure

CAS No. : 32162-64-4

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Other Forms of R-(+)-Cotinine:

R-(+)-Cotinine 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

R-(+)-Cotinine ((+)-Cotinine), a Nicotine metabolite, lacks significant activity across a wide range of pharmacological targets. R-(+)-Cotinine can enhance the Ach-evoked current in human α7 nAChRs[1].

体外研究
(In Vitro)

R-(+)-Cotinine (1 μM) significantly enhances the Ach (40 μM)-evoked current in human α7 nAChRs[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

R-(+)-Cotinine 相关抗体:
体内研究
(In Vivo)

R-(+)-Cotinine (0.3-10 mg/kg; a single i.p.) enhances the effects of a subthreshold dose of Donepezil (0.5 mg/kg) on novel object recognition (NOR) performance[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

176.22

Formula

C10H12N2O
CAS 号
中文名称

R-(+)-可替宁；R-(+)-可替丁；R-(+)-可铁宁；R-(+)-可的宁
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

R-(+)-Cotinine 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

R-(+)-Cotinine32162-64-4(+)-Cotinine (R)-Cotinine (R)-NIH-10498R-(+)-可替宁R-(+)-可替丁R-(+)-可铁宁R-(+)-可的宁nAChRNicotinic acetylcholine receptorsInhibitorinhibitorinhibit

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