Animal-Free IL-1F10/IL-38 蛋白, Human (His)

IL-1F10/IL-38 Protein is a member of the interleukin 1 cytokine family that regulates adapted and innate immune responses^[1]. Animal-Free IL-1F10/IL-38 Protein, Human (His) is the recombinant human-derived animal-FreeIL-1F10/IL-38 protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free IL-1F10/IL-38 Protein, Human (His) is 152 a.a., with molecular weight of ~17.78 kDa.

L-1F10/IL-38 蛋白是属于 IL-1 家族的分泌细胞因子，具有免疫调节活性。IL-1F10/IL-38 蛋白单独不会诱导细胞因子的产生，但会减少 T 细胞响应热灭活白色念珠菌而产生的 IL22 和 IL17A。IL-1F10/IL-38 蛋白可减少 IL36G 诱导的外周血单核细胞产生 IL8。IL-1F10/IL-38 蛋白可增加细菌脂多糖 (LPS) 刺激的树突状细胞产生 IL6。IL-36R/IL1RL2 的配体^[3][4]。

Human

E. coli

C-His

AAI03967.1 (M1-W152)

84639  [NCBI]

MCSLPMARYYIIKYADQKALYTRDGQLLVGDPVADNCCAEKICTLPNRGLDRTKVPIFLGIQGGSRCLACVETEEGPSLQLEDVNIEELYKGGEEATRFTFFQSSSGSAFRLEAAAWPGWFLCGPAEPQQPVQLTKESEPSARTKFYFEQSW

Approximately 17.78 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a solution containing 1X PBS, pH 7.4, trehalose.

<0.1 EU per 1 μg of the protein by the LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.