IL1F10 - interleukin 1 family member 10 Gene

中文名称：白细胞介素 1 家族成员 10

种属: Homo sapiens

同用名: IL-38; FKSG75; IL1HY2; IL-1HY2; IL1-theta; FIL1-theta

基因 ID: 84639 | 基因类型: protein coding

关于 IL1F10

Cytogenetic location: 2q14.1 Genomic coordinates (GRCh38): 2:113,067,970-113,075,843 (from NCBI)

This gene has 3 transcripts (splice variants), 208 orthologues and 7 paralogues. Restricted expression toward skin (RPKM 1.0).

功能概要

该基因编码的蛋白质是白介素 1 细胞因子家族的成员。该基因和其他八个白细胞介素 1 家族基因在 2 号染色体上形成一个细胞因子基因簇。该细胞因子被认为参与白细胞介素 1 家族成员网络，以调节适应性和先天性免疫反应。已经报道了编码相同蛋白质的两种可变剪接的转录物变体。[RefSeq 提供，2008 年 7 月]

The protein encoded by this gene is a member of the interleukin 1 cytokine family. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. This cytokine is thought to participate in a network of interleukin 1 family members to regulate adapted and innate immune responses. Two alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008]

IL1F10 基因产物(2)

mRNA	Protein	Name
NM_032556.6	NP_115945.4	interleukin-1 family member 10
NM_173161.3	NP_775184.1	interleukin-1 family member 10

基因本体论

分子功能

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	32296183	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

IL1F10 蛋白结构

IL1

0
100
152 a.a.

蛋白主名

其他名称

interleukin-1 family member 10

FIL1 theta

重组 IL1F10 蛋白

目录号	产品名	蛋白编号	纯度
HY-P72570	IL-1F10/IL-38 Protein, Human	AAI03967.1 (M1-W152)	≥95%
HY-P76427	IL-1F10/IL-38 Protein, Human (P.pastoris, His)	Q8WWZ1 (M1-W152)	≥95%
HY-P700129AF	Animal-Free IL-1F10/IL-38 Protein, Human (His)	AAI03967.1 (M1-W152)	≥95%

关联疾病

疾病名称

别名

Psoriasis 11

PSORS11	Psoriasis Susceptibility 11
Psoriasis	Psoriasis Vulgaris
Psoriasis 11, Susceptibility To	Pv

Impetigo Herpetiformis

Psoriasis 14, Pustular

Generalized Pustular Psoriasis	Gpp
Ditra	Acrodermatitis Continua Of Hallopeau
Palmoplantar Pustulosis	PSORS14
Interleukin 36 Receptor Antagonist Deficiency	Psorp
Pustular Psoriasis 14	Deficiency Of Il-36r Antagonist
Acute Generalised Pustular Psoriasis	Deficiency Of The Interleukin-36 Receptor Antagonist
Generalized Pustular Psoriasis Of Von Zumbusch	Von Zumbusch Psoriasis
Deficiency Of Il-36ra	Psoriasis, Pustular, Generalized
Psoriasis, Pustular, Type 14	Pustulosis Of Palms And Soles
Acute Generalized Pustular Psoriasis	Palmoplantar Pustular Psoriasis
Pustulosis Palmaris Et Plantaris	Ppp - [Palmoplantar Pustulosis]
Pustular Psoriasis Of The Palms And Soles	Pustular Bacterid

Periostitis

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS06719	IL1F10 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Mus musculus	IL1F10	MGD	MGI:2652548
Bos taurus	IL1F10	VGNC	VGNC:52788
Canis familiaris	IL1F10	VGNC	VGNC:49108
Macaca mulatta	IL1F10	VGNC	VGNC:106172
Rattus norvegicus	IL1F10	RGD	RGD:1305635
Others	IL1F10	NCBI

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