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  3. ASB13 蛋白, Human (His)

ASB13 蛋白, Human (His)

目录号: HY-P7511
产品使用指南

ASB13 蛋白, Human (His)属于锚蛋白重复序列和含有 SOCS 盒蛋白 (ASB) 的蛋白质家族,N 端带有 His 标签。

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描述

ASB13 Protein, Human (His) belongs to the ankyrin repeat and SOCS box-containing (ASB) family of proteins, with an N-terminal His tag[1].

研究背景

锚蛋白重复序列和 SOCS 盒蛋白 13 是人类中由 ASB13 基因编码的蛋白质。ASB13 包含锚蛋白重复序列和 SOCS 框结构域。ASB13 作为干细胞因子 (SCF) 样 Elongin-Cullin-SOCS (ECS) E3 泛素-蛋白质连接酶复合物的底物识别部分发挥作用,该复合物仲裁靶蛋白的泛素化和随后的蛋白酶体降解[1]

种属

Human

表达系统

E. coli

标签

N-6*His

蛋白编号

Q8WXK3-1 (M1-N278)

基因 ID
蛋白结构
N-term
6*His
ASB13 (M1-N278)
Accession # Q8WXK3-1
C-term
同用名
rHuSB13, His; Ankyrin repeat and SOCS box protein 13; ASB13; SB13
氨基酸序列

HHHHHHMEPRAADGCFLGDVGFWVERTPVHEAAQRGESLQLQQLIESGACVNQVTVDSITPLHAASLQGQARCVQLLLAAGAQVDARNIDGSTPLCDACASGSIECVKLLLSYGAKVNPPLYTASPLHEACMSGSSECVRLLIDVGANLEAHDCHFGTPLHVACAREHLDCVKVLLNAGANVNAAKLHETALHHAAKVKNVDLIEMLIEFGGNIYARDNRGKKPSDYTWSSSAPAKCFEYYEKTPLTLSQLCRVNLRKATGVRGLEKIAKLNIPPRLIDYLSYN

分子量

Approximately 28.0 kDa

纯度

Greater than 80% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料
参考文献

ASB13 Protein, Human (His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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ASB13 Protein, Human (His)
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