ASB13 - ankyrin repeat and SOCS box containing 13 Gene

中文名称：含锚蛋白重复和 SOCS 盒 13

种属: Homo sapiens

关于 ASB13

功能概要

由该基因编码的蛋白质是锚蛋白重复序列和含有 SOCS 盒 (ASB) 的蛋白质家族的成员。它们包含锚蛋白重复序列和 SOCS 框域。 SOCS 盒用于将细胞因子信号转导抑制因子 (SOCS) 蛋白及其结合伙伴与 elongin B 和 C 复合物偶联，可能靶向它们进行降解。已经针对该基因描述了多个选择性剪接的转录物变体，包括蛋白质编码和非蛋白质编码。[RefSeq 提供，2010 年 11 月]

The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants, both protein-coding and not protein-coding, have been described for this gene. [provided by RefSeq, Nov 2010]