Cathepsin A 蛋白, Human (HEK293, His)

Cathepsin A protein is an important protective factor for β-galactosidase and neuraminidase, maintaining their stability and optimizing enzyme activity. Its carboxypeptidase activity expands its functional repertoire and can deamid tachykinins and participate in a variety of biochemical processes. Cathepsin A Protein, Human (HEK293, His) is the recombinant human-derived Cathepsin A, expressed by HEK293 , with C-6*His labeled tag. The total length of Cathepsin A Protein, Human (HEK293, His) is 452 a.a.,

组织蛋白酶 A 蛋白是β-半乳糖苷酶和神经氨酸酶活性所必需的重要保护因子。组织蛋白酶 A 与这些酶共同作用，在保持其稳定性和确保最佳酶活性方面发挥着关键作用。除了其保护功能外，该蛋白质还表现出羧肽酶活性，从而拓宽了其功能库。值得注意的是，组织蛋白酶 A 具有使速激肽脱酰胺的能力，展示了其参与多种生化过程。组织蛋白酶 A 的多方面作用强调了其在维持关键酶促过程的完整性和功能性方面的重要性，从而有助于细胞稳态。

Measured by its ability to cleave a colorimetric peptide substrate of 20 μM Mca-RPPGFSAFK(Dnp)-OH (HY-P3749) that incubate at room temperature for 5 minutes. The specific activity is 3621.65 pmol/min/ug.

Human

HEK293

C-6*His

P10619-1 (A29-Y480)

5476  [NCBI]

APDQDEIQRLPGLAKQPSFRQYSGYLKGSGSKHLHYWFVESQKDPENSPVVLWLNGGPGCSSLDGLLTEHGPFLVQPDGVTLEYNPYSWNLIANVLYLESPAGVGFSYSDDKFYATNDTEVAQSNFEALQDFFRLFPEYKNNKLFLTGESYAGIYIPTLAVLVMQDPSMNLQGLAVGNGLSSYEQNDNSLVYFAYYHGLLGNRLWSSLQTHCCSQNKCNFYDNKDLECVTNLQEVARIVGNSGLNIYNLYAPCAGGVPSHFRYEKDTVVVQDLGNIFTRLPLKRMWHQALLRSGDKVRMDPPCTNTTAASTYLNNPYVRKALNIPEQLPQWDMCNFLVNLQYRRLYRSMNSQYLKLLSSQKYQILLYNGDVDMACNFMGDEWFVDSLNQKMEVQRRPWLVKYGDSGEQIAGFVKEFSHIAFLTIKGAGHMVPTDKPLAAFTMFSRFLNKQPY

51-60 kDa

• 
  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4, 8% trehalose.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping with dry ice.