COL4A3 蛋白, Rat (HEK293, Fc)

The COL4A3 protein is a key type IV collagen component that forms the major structural element of the glomerular basement membrane (GBM). It collaborates with laminin, proteoglycans, and nestin/nesidin to create a "chicken wire" network that is critical for maintaining the structural integrity of the GBM. COL4A3 Protein, Rat (HEK293, Fc) is the recombinant rat-derived COL4A3 protein, expressed by HEK293 , with N-hFc labeled tag. The total length of COL4A3 Protein, Rat (HEK293, Fc) is 245 a.a., with molecular weight of ~59 kDa.

COL4A3 蛋白是 IV 型胶原蛋白的重要组成部分，是肾小球基底膜 (GBM) 的主要结构元件，它与层粘连蛋白、蛋白聚糖和巢蛋白/巢蛋白合作创建“鸡丝”网络。这种复杂的网络在维持 GBM 的结构完整性和稳定性方面发挥着基础作用，这对于它们在肾脏生理学中的正常功能至关重要。COL4A3 参与网状结构的形成强调了其在支持肾小球基底膜完整性方面的重要性，肾小球基底膜对于肾功能和体内平衡至关重要。

Rat

HEK293

N-hFc

F1LRJ1 (G1426-H1670)

363265  [NCBI]

Approximately 59 kDa

Greater than 85% as determined by reducing SDS-PAGE

溶液.

Supplied as a 0.22 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.