FGFRL1 蛋白, Mouse (HEK293, His)

FGFRL1 protein significantly inhibits cell proliferation by interacting with FGF2 with low affinity, thereby regulating the proliferative signals associated with FGF2. This unique property positions FGFRL1 as a modulator of cellular growth, highlighting its intricate involvement in maintaining cellular homeostasis. FGFRL1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived FGFRL1 protein, expressed by HEK293 , with C-His labeled tag. The total length of FGFRL1 Protein, Mouse (HEK293, His) is 354 a.a., with molecular weight of ~55-68 KDa.

FGFRL1 是细胞动力学的关键参与者，对细胞增殖产生显着的负面影响。它与 FGF2 相互作用的特点是亲和力低，强调了它在减轻与 FGF2 相关的增殖信号方面的调节作用。这一独特的特性使 FGFRL1 成为细胞生长过程的调节剂，揭示了它在细胞稳态中的复杂参与。

Immobilized human bFGF at 5 μg/mL (100 μL/well) can bind mouse FGFR5. The ED₅₀ for this effect is 0.9066 μg/mL.

Mouse

HEK293

C-His

Q91V87 (A21-P374)

116701  [NCBI]

ARGPPRMADKVVPRQVARLGRTVRLQCPVEGDPPPLTMWTKDGRTIHSGWSRFRVLPQGLKVKEVEAEDAGVYVCKATNGFGSLSVNYTLIIMDDISPGKESPGPGGSSGGQEDPASQQWARPRFTQPSKMRRRVIARPVGSSVRLKCVASGHPRPDIMWMKDDQTLTHLEASEHRKKKWTLSLKNLKPEDSGKYTCRVSNKAGAINATYKVDVIQRTRSKPVLTGTHPVNTTVDFGGTTSFQCKVRSDVKPVIQWLKRVEYGSEGRHNSTIDVGGQKFVVLPTGDVWSRPDGSYLNKLLISRARQDDAGMYICLGANTMGYSFRSAFLTVLPDPKPPGPPMASSSSSTSLPWP

Approximately 55-68 kDa.

Greater than 95% as determined by reducing SDS-PAGE

无菌粉末

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.