Islet cell autoantigen 1/ICA1, Human (P.pastoris, His)

ICA1 may be involved in neurotransmitter secretion, suggesting involvement in synaptic transmission. It may help regulate the release of neurotransmitters, a key aspect of neuronal communication. Islet cell autoantigen 1/ICA1, Human (P.pastoris, His) is the recombinant human-derived Islet cell autoantigen 1/ICA1, expressed by P. pastoris , with N-6*His labeled tag. The total length of Islet cell autoantigen 1/ICA1, Human (P.pastoris, His) is 482 a.a., with molecular weight of ~62 kDa.

胰岛细胞自身抗原 1 (ICA1) 被认为可能在神经递质分泌中发挥作用，突显其参与与突触传递相关的复杂过程。功能意义表明 ICA1 可能有助于调节神经递质的释放，这是神经元通讯的一个关键方面。ICA1 调节神经递质分泌的具体机制及其在突触功能中的精确作用仍然是人们感兴趣的领域，需要进一步探索以阐明其在神经元过程和神经系统内通讯背景下的功能意义和分子贡献。

Human

P. pastoris

N-6*His

Q05084-3 (M1-A482)

3382  [NCBI]

MSGHKCYPWDLQDRYAQDKSVVNKMQQKYWETKQAFIKATGKKEDEHVVASDADLDAKLELFHSIQRTCLDLSKAIVLYQKRICFLSQEENELGKFLRSQGFQDKTRAGKMMQATGKALCFSSQQRLALRNPLCRFHQEVETFRHRAISDTWLTVNRMEQCRTEYRGALLWMKDVSQELDPDLYKQMEKFRKVQTQVRLAKKNFDKLKMDVCQKVDLLGASRCNLLSHMLATYQTTLLHFWEKTSHTMAAIHESFKGYQPYEFTTLKSLQDPMKKLVEKEEKKKINQQESTDAAVQEPSQLISLEEENQRKESSSFKTEDGKSILSALDKGSTHTACSGPIDELLDMKSEEGACLGPVAGTPEPEGADKDDLLLLSEIFNASSLEEGEFSKEWAAVFGDGQVKEPVPTMALGEPDPKAQTGSGFLPSQLLDQNMKDLQASLQEPAKAASDLTAWFSLFADLDPLSNPDAVGKTDKEHELLNA

Approximately 62 kDa

Greater than 90% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm sterile filtered 20 mM Tris-HCl, 0.5 M NaCl, 3% Trehalose, pH 8.0.

<1.0 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.