LILRA5/CD85f 蛋白, Rat (HEK293, His)

The LILRA5/CD85f protein is predicted to have inhibitory MHC class I receptor activity and may modulate immune responses. Involved in the MAPK cascade and regulation of cytokine production, expected to be active on the cell surface and extracellular space, and in the plasma membrane. LILRA5/CD85f Protein, Rat (HEK293, His) is the recombinant rat-derived LILRA5/CD85f protein, expressed by HEK293 , with C-His labeled tag. The total length of LILRA5/CD85f Protein, Rat (HEK293, His) is 232 a.a., with molecular weight of ~37 kDa.

LILRA5/CD85f 蛋白预计具有抑制性 MHC I 类受体活性，表明其在免疫调节中的潜在作用。该蛋白预计参与 MAPK 级联的正向调节、蛋白酪氨酸激酶活性的正向调节以及细胞因子产生的调节等过程，预计位于细胞表面和细胞外空间，预计其活性在质膜。LILRA5 与包括 LILRA5（白细胞免疫球蛋白样受体 A5）在内的多个人类基因是直系同源的，表明其功能的进化保守性。该蛋白表现出偏向表达，在脾脏 (RPKM 160.9)、肝脏 (RPKM 62.0) 和其他七个组织中观察到显着水平，强调了其在各种组织的免疫相关过程中的潜在重要性。

Measured by its binding ability in a functional ELISA. When Recombinant Human LILRA5/CD85f is coated at 2 µg/mL can bind ANGPTL7. The ED₅₀ for this effect is 0.5874 μg/mL.

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  Measured by its binding ability in a functional ELISA. When Recombinant Human LILRA5/CD85f is coated at 2 µg/mL can bind ANGPTL7. The ED₅₀ for this effect is 0.5874 μg/mL.

Rat

HEK293

C-His

NP_001070261.1 (Q17-N248)

691533  [NCBI]

QETSGLEGNPHKPTLSVQPGSLVARGKQVTILCEVTTGAQEYRLFKEGGPHPWRTKNTPKATNKAQFLISSIEQQHGGIYRCYYKTPSGWSEHSDPLELVVTGLYSKPSLSIQSSTVVTSGETVTLQCVSQLGFNRFVLTKEGEQKPSLIRDSEFINSTGQFQGLFPMGPVILSQRWMFRCYGYYVNSPQVWSEPSDLLEIHVSEAAQPLGLSPNISHPKTVSQHQDYTMEN

Approximately 33-40 kDa due to the glycosylation

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  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.