1. 重组蛋白
  2. Receptor Proteins
  3. OX1R 蛋白, Human (HEK293, FLAG, His)

OX1R 蛋白, Human (HEK293, FLAG, His)

目录号: HY-P701836
产品使用指南

OX1R 是一种中等选择性兴奋性受体,可结合食欲素 A 和食欲素 B 神经肽。与 orexin-A 结合后,OX1R 激活细胞事件,提高细胞质 Ca(2+) 水平。这种相互作用将 OX1R 定位为食欲素神经肽信号传导的介质,影响食欲素-A 响应的细胞内钙动态。OX1R 蛋白, Human (HEK293, FLAG, His) 是重组的 OX1R 蛋白,由 HEK293 表达,带有 C-10*His, N-Flag 标签。OX1R 蛋白, Human (HEK293, FLAG, His) 。

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描述

OX1R, a moderately selective excitatory receptor, binds orexin-A and orexin-B neuropeptides. Upon orexin-A binding, OX1R activates cellular events, elevating cytoplasmic Ca(2+) levels. This interaction positions OX1R as a mediator in orexin neuropeptide signaling, influencing intracellular calcium dynamics in response to orexin-A. OX1R Protein, Human (HEK293, FLAG, His) is the recombinant human-derived OX1R protein, expressed by HEK293 , with C-10*His, N-Flag labeled tag. ,

研究背景

OX1R 是一种中等选择性兴奋性受体,对食欲素 A 和食欲素 B 神经肽均具有亲和力。与食欲素-A 结合后,OX1R 启动一系列细胞事件,导致细胞质 Ca(2+) 水平升高。这种相互作用凸显了 OX1R 作为食欲素神经肽信号传导介质的作用,有助于调节细胞内钙动态以响应食欲素-A 结合。

种属

Human

表达系统

HEK293

标签

C-10*His;N-Flag

蛋白编号

O43613

基因 ID

3061

蛋白结构
N-term
Flag

Accession # O43613
10*His OX1R
C-term
同用名
HCRTR1; Orexin/Hypocretin receptor type 1; Hypocretin receptor type 1; Orexin receptor type 1; Ox-1-R; Ox1-R; Ox1R
纯度

Greater than 90% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

OX1R Protein, Human (HEK293, FLAG, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
OX1R Protein, Human (HEK293, FLAG, His)
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HY-P701836
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