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  4. ZFAND3 蛋白, Human (Sf9, His, Strep)

ZFAND3 蛋白, Human (Sf9, His, Strep)

目录号: HY-P701602
产品使用指南

ZFAND3 是一种转录调节蛋白，可调节粘附和侵袭相关基因的表达，能够驱动胶质母细胞瘤的侵袭。此外，ZFAND3 还能通过改善胰岛素抵抗和抑制糖异生来改善糖耐量，被确定为 2 型糖尿病的易感基因。ZFAND3 蛋白, Human (Sf9, His, Strep) 是重组的 ZFAND3 蛋白，由 Sf9 insect cells 表达，带有 N-Strep, N-8*His 标签。ZFAND3 蛋白, Human (Sf9, His, Strep) 全长 226 个氨基酸。

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描述

ZFAND3 is a transcriptional regulatory protein that regulates the expression of adhesion and invasion related genes, and can drive the invasion of glioblastoma. In addition, ZFAND3 can improve glucose tolerance by improving insulin resistance and inhibiting gluconeogenesis, and is identified as a susceptibility gene for type 2 diabetes. ZFAND3 Protein, Human (Sf9, His, Strep) is the recombinant human-derived ZFAND3 protein, expressed by Sf9 insect cells , with N-Strep, N-8*His labeled tag. The total length of ZFAND3 Protein, Human (Sf9, His, Strep) is 226 a.a., .
研究背景

ZFAND3 是一种转录调节蛋白，可调节粘附和侵袭相关基因的表达，能够驱动胶质母细胞瘤的侵袭。ZFAND3 在核蛋白复合物中发挥作用，激活基因转录，并调节与侵袭相关的基因 (如 COL6A2、FN1 和NRCAM) 的启动子。此外，ZFAND3 还能通过改善胰岛素抵抗和抑制糖异生来改善糖耐量，被确定为 2 型糖尿病的易感基因[1][2]。
种属

Human
表达系统

Sf9 insect cells
标签

N-Strep;N-8*His
蛋白编号

Q9H8U3 (G2-S227)
基因 ID

60685
蛋白结构
N-term
8*His-Strep
ZFAND3 (G2-S227)
Accession # Q9H8U3
C-term
同用名
ZFAND3; AN1-type zinc finger protein 3; Testis-expressed protein 27
纯度

Greater than 90% as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

ZFAND3 Protein, Human (Sf9, His, Strep) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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