2. Neuronal Signaling
  3. Huntingtin
  4. Rovanersen sodium

Rovanersen sodium  (Synonyms: WVE-120101 sodium)

目录号: HY-132593A 纯度: 94.24%
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摩尔计算器

Rovanersen sodium 是一种反义寡核苷酸，通过特异靶向 huntingtin (HTT) 基因的突变 mRNA 拷贝，而不影响正常的 HTT 基因的 mRNA，从而防止有缺陷的 huntingtin 蛋白的产生。Rovanersen sodium 可用于亨廷顿病的研究。

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DNA,d(rGm-[P(S)]-sp-rGm-rCm-rAm-rCm-[P(S)]-sp-A-[P(S)]-sp-A-[P(S)]-sp-G-[P(S)]-sp-G-[P(S)]-sp-G-[P(S)]-sp-C-[P(S)]-sp-A-[P(S)]-sp-C-[P(R)]-sp-A-[P(S)]-sp-G-[P(S)]-sp-rAm-rCm-rUm-rUm-[P(S)]-sp-rCm), sodium salt

Rovanersen sodium Chemical Structure

CAS No. : 2231347-41-2

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规格 价格 是否有货 数量
1 mg ￥670
In-stock
5 mg ￥1760
In-stock
10 mg ￥2910
In-stock
25 mg ￥4370
In-stock
50 mg   询价  
100 mg   询价  

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Other Forms of Rovanersen sodium:

Rovanersen sodium 相关抗体

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  • 生物活性

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  • 参考文献

生物活性

Rovanersen sodium is an antisense oligonucleotide that specifically targets mutated mRNA copies of the huntington (HTT) gene without affecting healthy mRNA of HTT gene, thereby preventing the production of faulty Huntingtin protein. Rovanersen sodium can be used for huntington’s disease research[1].

分子量

7034.70

Formula

C202H240N82Na19O111P19S13
CAS 号
性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, stored under nitrogen, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)

纯度 & 产品资料
参考文献

Rovanersen sodium 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

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Keywords:

Rovanersen2231347-41-2WVE-120101WVE120101WVE 120101Huntingtinantisenseoligonucleotidehuntington’sdiseaseInhibitorinhibitorinhibit

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