2. Immunology/Inflammation
  3. Tim3
  4. Sabatolimab

Sabatolimab  (Synonyms: MBG453)

目录号: HY-P99044 纯度: 99.15%
COA

摩尔计算器

Sabatolimab (MBG453) 是一种高亲和力的人源化 IgG4 (S228P) 抗体，靶向 TIM-3，一种调节适应性和先天免疫反应的抑制性受体。Sabatolimab 是一种潜在的免疫抑制活性分子，可以靶向免疫细胞和骨髓细胞上的 TIM-3。

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CAS No. : 2252262-24-9

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规格 价格 是否有货 数量
1 mg ￥1890
In-stock
5 mg ￥5300
In-stock
10 mg ￥9050
In-stock
50 mg   询价  
100 mg   询价  

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Customer Review

Sabatolimab 相关抗体

Top Publications Citing Use of Products

MCE 顾客使用本产品发表的 1 篇科研文献

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Sabatolimab (MBG453) is a high-affinity, humanized, IgG4 (S228P) antibody targeting TIM-3, an inhibitory receptor that regulates adaptive and innate immune responses. Sabatolimab is a potential immunosuppression agent that can target TIM-3 on immune and myeloid cells[1].

同型

Human IgG4 (S228P) kappa
推荐同型对照抗体
种属

Humanized
Clinical Trial
CAS 号
性状

液体

颜色

Colorless to light yellow

运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Human IgG4 kappa
Biological Activity
  • Loaded TIM-3/HAVCR2 Protein, Human (Biotinylated, HEK293, His-Avi,HY-P78217) on AHC2 biosensor, can bind Sabatolimab with an affinity constant of 8.541E-11 M as determined in BLI assay.
纯度 & 产品资料

纯度: 99.15%

COA (264 KB) SDS-PAGE (276 KB) SEC-HPLC (462 KB)

抗体抑制剂使用指南 (1152 KB)
参考文献

Sabatolimab 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sabatolimab2252262-24-9MBG453MBG 453MBG-453Tim3T-Cell Immunoglobulin and Mucin Containing Protein-3CD366humanizedIgG4S228PantibodyTIM-3adaptiveinnate immuneimmunosuppression agentmyeloid cellsInhibitorinhibitorinhibit

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