1. GPCR/G Protein Neuronal Signaling
  2. Somatostatin Receptor
  3. SSTR5 antagonist 3

SSTR5agonist 3 (Compound 23) 是一种生长抑素受体亚型 5 (SSTR5) 拮抗剂,具有低 hERG 抑制作用和口服有效性。SSTR5agonist 3 在人和小鼠中的 IC50 值分别为 2.8 nM 和 1.4 nM。SSTR5agonist 3 可用于抗胆结石的研究。

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SSTR5 antagonist 3 Chemical Structure

SSTR5 antagonist 3 Chemical Structure

CAS No. : 2851454-42-5

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生物活性

SSTR5 antagonist 3 (Compound 23) is an orally active somatostatin receptor subtype 5 (SSTR5) antagonist with low hERG inhibition. SSTR5 antagonist 3 exhibits potency with IC50 values of 2.8 nM and 1.4 nM in human and mouse, respectively. SSTR5 antagonist 3 can be used for the research of anti-gallstone[1].

IC50 & Target

IC50: 2.8 nM (human); 1.4 nM (mouse)[1].

分子量

554.62

Formula

C31H36F2N2O5

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
SSTR5 antagonist 3
目录号:
HY-157303
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