2. Anti-infection
  3. Reverse Transcriptase
  4. Tenofovir diphosphate

Tenofovir diphosphate  (Synonyms: TFV-DP)

目录号: HY-136548
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摩尔计算器

Tenofovir diphosphate (TFV-DP) 是一种 ATP 竞争性的 DNA 聚合酶 (DNA polymerases) 抑制剂，且是 1 型 HIV (HIV-1) 逆转录酶 (RT) 的底物。

该游离形式化合物不稳定，推荐具有相同生物学活性的稳定盐形式 Tenofovir diphosphate disodium。

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Tenofovir diphosphate Chemical Structure

Tenofovir diphosphate Chemical Structure

CAS No. : 166403-66-3

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Tenofovir diphosphate 的其他形式现货产品:

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Other Forms of Tenofovir diphosphate:

Tenofovir diphosphate 相关抗体

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MCE 顾客使用本产品发表的 1 篇科研文献

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Tenofovir diphosphate (TFV-DP) is a competitive DNA polymerases inhibitor (with respect to dATP) and a substrate of HIV type 1 (HIV-1) reverse transcriptase (RT)[1].

IC50 & Target

DNA polymerases; HIV-1 reverse transcriptase[1]
体外研究
(In Vitro)

Tenofovir diphosphate acts as an inhibitor of DNA pol. Tenofovir-diphosphate is a weak inhibitor of DNA polymerases (pol) α, δ, and ɛ, with values for the Ki for PMPApp (PMPAppKi) relative to the Km for dATP (dATPKm) of 10.2, 10.2, and 15.6, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Tenofovir diphosphate 相关抗体:
分子量

447.17

Formula

C9H16N5O10P3
CAS 号
中文名称

替诺福韦二磷酸酯
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Tenofovir diphosphate 相关分类

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  • 稀释计算器

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  • Do most proteins show cross-species activity?

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Keywords:

Tenofovir diphosphate166403-66-3TFV-DP替诺福韦二磷酸酯Reverse TranscriptaseDNApolymerasessubstrateHIVHIV-1reversetranscriptaseInhibitorinhibitorinhibit

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