2. Anti-infection
  3. Bacterial
  4. Tetromycin A

Tetromycin A 是一种基于四氯酸的抗生素。据报道，它对革兰氏阳性菌（包括耐甲氧西林金黄色葡萄球菌）具有显著的活性。相关的四霉素衍生物被发现具有抗锥虫活性，并抑制半胱氨酸蛋白酶蛋白酶 L，Ki 值在低微摩尔范围内。

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Tetromycin A Chemical Structure

Tetromycin A Chemical Structure

CAS No. : 180027-83-2

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Tetromycin A 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Tetromycin A is a tetronic acid-based antibiotic. It reportedly has pronounced activity against Gram-positive bacteria, including methicillin-resistant S. aureus. Related tetromycin derivatives have been found to have anti-trypanosomal activity and inhibit the cysteine protease cathepsin L with Ki values in the low micromolar range.

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
NCI-H460 IC50
> 30 μM
Compound: 13
Cytotoxicity against human NCI-H460 cells and measured after 48 hrs by MTT assay
Cytotoxicity against human NCI-H460 cells and measured after 48 hrs by MTT assay
[PMID: 35640100]
SW-620 IC50
> 30 μM
Compound: 13
Cytotoxicity against human SW-620 cells and measured after 48 hrs by MTT assay
Cytotoxicity against human SW-620 cells and measured after 48 hrs by MTT assay
[PMID: 35640100]
分子量

576.76

Formula

C36H48O6
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Tetromycin A 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

Tetromycin A180027-83-2BacterialInhibitorinhibitorinhibit

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