2. Cell Cycle/DNA Damage Cytoskeleton Apoptosis
  3. Microtubule/Tubulin Apoptosis
  4. Tubulin polymerization-IN-45

Tubulin polymerization-IN-45 是一种微管蛋白靶向剂，是一种微管蛋白聚合 (tubulin polymerization) 抑制剂。Tubulin polymerization-IN-45 与微管蛋白的秋水仙碱位点结合， 诱导肝细胞癌细胞 (HCC) 细胞凋亡 (apoptosis)。

MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务

Tubulin polymerization-IN-45 Chemical Structure

Tubulin polymerization-IN-45 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 mg   询价  
100 mg   询价  
250 mg   询价  

* Please select Quantity before adding items.

Customer Review

Tubulin polymerization-IN-45 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Tubulin polymerization-IN-45, a tubulin-targeting agent, is a tubulin polymerization inhibitor. Tubulin polymerization-IN-45 binds to the colchicine site of tubulin. Tubulin polymerization-IN-45 induces apoptotic cell death in hepatocellular cancer (HCC) cells[1].

体外研究
(In Vitro)

Tubulin polymerization-IN-45（化合物 18）显示出针对肝细胞癌 (HCC) 细胞系的有效活性，IC50 值在 0.6-2.9 μM 范围内。Tubulin polymerization-IN-45 还表现出对微管蛋白聚合的中等抑制活性 (IC50= 19 μM)。Tubulin polymerization-IN-45 导致 Huh7 和 Mahlavu 细胞的细胞周期停滞在 G2/M 期，并诱导 HCC 细胞凋亡[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Tubulin polymerization-IN-45 相关抗体:
分子量

362.38

Formula

C20H18N4O3
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Tubulin polymerization-IN-45 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tubulin polymerization-IN-45Microtubule/TubulinApoptosistubulin-targeting agenttubulin polymerization inhibitorcolchicine sitecell cycle arrestInhibitorinhibitorinhibit

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称：

  

* 需求量：

* 客户姓名：

 

* Email：

* 电话：

 

* 公司或机构名称：

   留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
Tubulin polymerization-IN-45
目录号：
HY-155139
需求量：

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

   产品名称：

  

* Lot #：

* 客户姓名：

 

* Email：

   电话：

 

* 部门：

* 公司或机构名称：

 

   留言给我们：

Request for HNMR Report

We have received your request and will respond to you as soon as possible.

嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z