1. Immunology/Inflammation
  2. CD47 Interleukin Related
  3. Urabrelimab

Urabrelimab  (Synonyms: SRF-231; SRF231)

目录号: HY-P99533 纯度: 98.49%
COA

Urabrelimab (SRF231) 是一种完全人抗 CD47 单克隆抗体,可阻断 CD47-SIRP 相互作用。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

CAS No. : 2249722-58-3

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 价格 是否有货 数量
1 mg ¥2500
In-stock
5 mg ¥7000
In-stock
10 mg   询价  
50 mg   询价  

* Please select Quantity before adding items.

Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Urabrelimab (SRF231) is a fully human anti-CD47 monoclonal antibody that blocks the CD47-SIRP interaction[1].

同型

Human IgG4 kappa

推荐同型对照抗体
种属

Human

体外研究
(In Vitro)

Urabrelimab (SRF231) 在体外促进巨噬细胞介导的对几种血液原发肿瘤样本和细胞系的吞噬清除。Urabrelimab 增加 Raji 肿瘤细胞系靶细胞的吞噬作用,EC50 为 ~300 ng/mL[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

体内研究
(In Vivo)

Urabrelimab (SRF231) 在多发性骨髓瘤、弥漫性大 B 细胞淋巴瘤和伯基特淋巴瘤模型中作为单一药物和与调理抗体联合使用可导致显著的肿瘤生长抑制。在 Raji 异种移植模型中,单药处理可抑制 112% 的肿瘤生长[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
CAS 号
性状

液体

颜色

Colorless to light yellow

运输条件

Shipping with dry ice.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

Format
  • Human IgG4 kappa
纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
Urabrelimab
目录号:
HY-P99533
需求量: