2. GPCR/G Protein
  3. Angiotensin Receptor
  4. Valsartan methyl ester (Standard)

Valsartan methyl ester (Standard) 

目录号: HY-W414915R 纯度: ≥98%
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Valsartan methyl ester (Standard)是 Valsartan methyl ester 的分析标准品。本产品用于研究及分析应用。Valsartan methyl ester (Compound 3) 是 Valsartan (HY-18204) 的衍生物。Valsartan methyl ester 是口服有效的血管紧张素 II (angiotensin II) 拮抗剂，抑制血管紧张素 II (IC50 为 0.06 μM)，抑制血管紧张素 II 诱导的兔主动脉升压反应 (IC50 为 0.068 μM) 和血管紧张素 II 在大鼠模型中诱导的升压反应 (10 mg/kg，口服，抑制率为 10%)。

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Valsartan methyl ester (Standard) Chemical Structure

Valsartan methyl ester (Standard) Chemical Structure

CAS No. : 137863-17-3

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生物活性

Valsartan methyl ester (Standard) is the analytical standard of Valsartan methyl ester. This product is intended for research and analytical applications. Valsartan methyl ester (Compound 3) is a derivative of Valsartan (HY-18204). Valsartan methyl ester is an orally active antagonist for angiotensin II, that inhibits angiotensin II (IC50 of 0.06 μM), angiotensin II-induced pressor response in rabbit aorta (IC50 of 0.068 μM) and angiotensin II-induced pressor response in the pithed rat model (10% inhibition at 10 mg/kg, p.o.).

分子量

449.55

Formula

C25H31N5O3
CAS 号
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

Valsartan methyl ester (Standard) 相关分类

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Keywords:

Valsartan methyl ester (Standard)137863-17-3Angiotensin ReceptorHypertensioncongestive heart failureInhibitorinhibitorinhibit

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