2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite Phosphodiesterase (PDE)
  4. Vardenafil (dihydrochloride) (Standard)

Vardenafil (dihydrochloride) (Standard)  (Synonyms: 伐地那非（盐酸盐） (Standard))

目录号: HY-B0442CR 纯度: ≥98%
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摩尔计算器

Vardenafil (dihydrochloride) (Standard)是 Vardenafil (dihydrochloride) 的分析标准品。本产品用于研究及分析应用。Vardenafil dihydrochloride 是一种具有高选择性和口服活性的磷酸二酯酶 5 (PDE5) 抑制剂，IC50 为 0.7 nM。Vardenafil dihydrochloride 对 PDE1、PDE6 的 IC50 分

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Vardenafil (dihydrochloride) (Standard) Chemical Structure

Vardenafil (dihydrochloride) (Standard) Chemical Structure

CAS No. : 224789-15-5

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生物活性

Vardenafil (dihydrochloride) (Standard) is the analytical standard of Vardenafil (dihydrochloride). This product is intended for research and analytical applications. Vardenafil dihydrochloride is a selective and orally active inhibitor of phosphodiesterase-5 (PDE5), with an IC50 of 0.7 nM. Vardenafil dihydrochloride shows inhibitory towards PDE1, PDE6 with IC50s of 180 nM, and 11 nM respectively, while IC50s are >1000 nM for PDE3 and PDE4. Vardenafil dihydrochloride competitively inhibits cyclic guanosine monophosphate (cGMP) hydrolysis and thus increases cGMP levels. Vardenafil dihydrochloride can be used for the research of erectile dysfunction, hepatitis, diabetes-.

分子量

561.52

Formula

C23H34Cl2N6O4S
CAS 号
中文名称

伐地那非（盐酸盐） (Standard)
结构分类
初始来源
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

Vardenafil (dihydrochloride) (Standard) 相关分类

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  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Vardenafil (dihydrochloride) (Standard)224789-15-5伐地那非（盐酸盐） (Standard)Endogenous MetabolitePhosphodiesterase (PDE)cGMPselectivesmoothmuscleNOstimulationerectiledysfunctionvardenafilimpotencePharmacokineticserectile dysfunctionhepatitiszucker diabetic fatty ratsdiabetesInhibitorinhibitorinhibit

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