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  4. VEC6

VEC6 (NSC 11435)是一种VEZF1–DNA相互作用抑制剂，具有在缺血性视网膜病中重现RhoB缺失的活性。VEC6可降低病理性血管生成，并促进淋巴管生成。VEC6通过调控内皮细胞的不同基因集表达，在血管和淋巴管生成过程中发挥独特的作用。VEC6对VEZF1介导的转录活性具有抑制作用，从而影响内皮细胞的增殖和分芽。

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VEC6 Chemical Structure

VEC6 Chemical Structure

CAS No. : 3431-16-1

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VEC6 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

VEC6 (NSC 11435) is an inhibitor of VEZF1–DNA interaction and has the activity to recapitulate RhoB loss in ischemic retinopathy. VEC6 reduces pathological angiogenesis and promotes lymphangiogenesis. VEC6 plays a unique role in angiogenesis and lymphangiogenesis by regulating the expression of different sets of genes in endothelial cells. VEC6 has an inhibitory effect on VEZF1-mediated transcriptional activity, thereby affecting the proliferation and sprouting of endothelial cells[1].

分子量

244.34

Formula

C14H20N4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

VEC6 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

VEC63431-16-1NSC 11435VEC 6VEC-6NSC11435NSC-11435OthersInhibitorinhibitorinhibit

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