2. Immunology/Inflammation
  3. CD3
  4. Vepsitamab

Vepsitamab  (Synonyms: 维斯妥单抗; AMG 199)

目录号: HY-P99523 纯度: 98.44%
COA

摩尔计算器

Vepsitamab (AMG 199) 是一种抗 MUC17/CD3 BiTE 抗体，可以结合 T 细胞上的 CD3 和肿瘤细胞上表达的 MUC17，介导重定向的肿瘤细胞裂解，并诱导 T 细胞活化和增殖。

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CAS No. : 2413453-53-7

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规格 价格 是否有货 数量
1 mg ￥6500
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Vepsitamab 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Vepsitamab (AMG 199) is an anti-MUC17/CD3 BiTE antibody that binds to CD3 on T cells and MUC17 expressed on tumor cells, mediates redirected tumor cell lysis, and induces T cell activation and proliferation[1].

同型

(scFv-heavy-lambda)-(scFv-heavy-lambda)-scFc
种属

Chimeric; Humanized
Clinical Trial
CAS 号
性状

液体

颜色

Colorless to light yellow

中文名称

维斯妥单抗
运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • (scFv-heavy-lambda)-(scFv-heavy-lambda)-scFc
Biological Activity
  • Immobilized Vepsitamab can bind Human MUC17 Protein (His Tag). The EC50 for this effect is 2.10 ng/mL.
  • Immobilized Vepsitamab can bind Human CD3 epsilon/CD3e Protein (ECD, His Tag). The EC50 for this effect is 2.35 ng/mL.
纯度 & 产品资料
参考文献

Vepsitamab 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Vepsitamab2413453-53-7AMG 199维斯妥单抗AMG199AMG-199CD3Cluster of differentiation 3MUC17tumorT cellsInhibitorinhibitorinhibit

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目录号：
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