2. Metabolic Enzyme/Protease
  3. Xanthine Oxidase
  4. Xanthine oxidoreductase-IN-4

Xanthine oxidoreductase-IN-4 是一种黄嘌呤氧化还原酶 (XOR) 抑制剂，具有口服活性。Xanthine oxidoreductase-IN-4 对 XOR 具有抑制活性，IC50 值为 29.3 nM。Xanthine oxidoreductase-IN-4 可用于高尿酸血症的研究。

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Xanthine oxidoreductase-IN-4 Chemical Structure

Xanthine oxidoreductase-IN-4 Chemical Structure

CAS No. : 1026587-58-5

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Xanthine oxidoreductase-IN-4 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Xanthine oxidoreductase-IN-4 is an orally active xanthine oxidoreductase (XOR) inhibitor. Xanthine oxidoreductase-IN-4 has inhibitory activity against XOR with an IC50 value of 29.3 nM. Xanthine oxidoreductase-IN-4 can be used for the research of hyperuricemia[1].

IC50 & Target

IC50: 29.3 nM (XOR)[1]
体外研究
(In Vitro)

Xanthine oxidoreductase-IN-4 (Compound IIIc) 对 XOR 具有抑制活性，IC50 值为 29.3 nM[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Xanthine oxidoreductase-IN-4 相关抗体:
体内研究
(In Vivo)

Xanthine oxidoreductase-IN-4 (Compound IIIc) (oral; 5 mg/kg)在恶嗪酸钾/次黄嘌呤诱导的急性高尿酸血症模型中显示出显着的低尿酸血症效应[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Mice acute hyperuricemia model[1]
Dosage: 5 mg/kg
Administration: Oral
Result: Reduced serum levels of uric acid significantly from 4 h after administration.
分子量

309.32

Formula

C16H15N5O2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Xanthine oxidoreductase-IN-4 相关分类

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Keywords:

Xanthine oxidoreductase-IN-41026587-58-5Xanthine OxidaseXOxanthine oxidoreductase (XOR)HypouricemicPhenyl-tetrazoleInhibitorinhibitorinhibit

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