2. Neuronal Signaling
  3. α-synuclein
  4. α-Synuclein 4554W

α-Synuclein 4554W 是一种α-Synuclein (aSyn) 聚集抑制剂，具有相关毒性。α-突触核蛋白 4554W 由 GIVNGVKA 序列组成，这些序列先前通过细胞内文库筛选鉴定。α-突触核蛋白 4554W 减少与帕金森病相关的 aSyn 突变体的原纤维形成。

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Custom Peptide Synthesis

α-Synuclein 4554W Chemical Structure

α-Synuclein 4554W Chemical Structure

CAS No. : 2243207-00-1

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α-Synuclein 4554W 相关抗体

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生物活性

α-Synuclein 4554W is an inhibitor of α-Synuclein (aSyn) aggregation with associated toxicity. α-Synuclein 4554W consists of GIVNGVKA sequences, previously identified through intracellular library screening. α-Synuclein 4554W reduces fibril formation of aSyn mutants assocaited with Parkinson’s disease[1].

分子量

1041.20

Formula

C45H80N14O14
CAS 号
Sequence

Ac-Lys-Asp-Gly-Ile-Val-Asn-Gly-Val-Lys-Ala-NH2
Sequence Shortening

Ac-KDGIVNGVKA-NH2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

α-Synuclein 4554W 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

α-Synuclein 4554W2243207-00-1α-synucleinα-SynaSyn aggregationfibril formationaSyn mutantsParkinson’s diseaseInhibitorinhibitorinhibit

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