1. 寡核苷酸
  2. 帽类似物
  3. Cap 0
  4. β-S-ARCA

β-S-ARCA 是一种 mRNA 7- 甲基鸟苷 (m7G) 帽结构的类似物,携带硫代磷酸化部分。结合 β-S-ARCA 的 mRNA 延长了细胞半衰期,增加了蛋白表达。β-S-ARCA D1 已应用于研究基于 mRNA 的实验性抗癌疫苗。

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5′-Guanylic acid, 7-methyl-2′-O-methyl-, inner salt, P′-anhydride with 5′-guanylic acid monoanhydride with phosphorothioic acid

β-S-ARCA Chemical Structure

CAS No. : 1093268-63-3

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β-S-ARCA 的其他形式现货产品:

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Other Forms of β-S-ARCA:

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

β-S-ARCA is a mRNA 7-methylguanosine (m7G) cap analog carrying a phosphorothioate (PS) moiety. mRNAs incorporating β-S-ARCA have elongated cellular half-lives and showed augmented protein expression. β-S-ARCA D1 has been applied in researching experimental mRNA-based anticancer vaccines[1].

分子量

832.52

Formula

C22H31N10O17P3S

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

β-S-ARCA 相关分类

  • 摩尔计算器

  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
β-S-ARCA
目录号:
HY-145969
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