1. Epigenetics Protein Tyrosine Kinase/RTK JAK/STAT Signaling Stem Cell/Wnt Apoptosis
  2. JAK Apoptosis
  3. Bayer-18

Bayer-18 是 TYK2 的抑制剂。Bayer-18 抑制间变性大细胞淋巴瘤细胞 K299,SR786,Mac1 和 Mac2a 活力,IC50 为 2-3 µM,并在 K299 和 SR786 细胞中诱导凋亡 (apoptosis)。

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Bayer-18 Chemical Structure

Bayer-18 Chemical Structure

CAS No. : 1251752-12-1

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  • 生物活性

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  • 参考文献

生物活性

Bayer-18 is an inhibitor for TYK2. Bayer-18 inhibits the viability of ALCL cell K299, SR786, Mac1 and Mac2a with IC50 of 2-3 µM, and induces apoptosis in K299 and SR786[1].

IC50 & Target

Tyk2

 

分子量

390.46

Formula

C19H27FN6O2

CAS 号
性状

固体

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料
参考文献
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  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Bayer-18
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HY-18315
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