2. Anti-infection Neuronal Signaling
  3. Bacterial Cholinesterase (ChE)
  4. Dimethyl sulfoxide, meets analytical specification of Ch.P.

Dimethyl sulfoxide, meets analytical specification of Ch.P.  (Synonyms: 二甲基亚砜, meets analytical specification of Ch.P.; DMSO, meets analytical specification of Ch.P.)

目录号: HY-Y0320 纯度: 99.89%
COA 产品使用指南 技术支持

Dimethyl sulfoxide (DMSO) 是一种非质子溶剂，可溶解极性和非极性化合物，包括不溶于水的治疗剂和毒性剂。Dimethyl sulfoxide (DMSO) 对水有很强的亲和力，可快速渗透或增强其他物质渗透生物膜。Dimethyl sulfoxide 还具有潜在清除自由基和抗胆碱酯酶的作用，并可能影响凝血活性。Dimethyl sulfoxide 还诱导肥大细胞释放组胺，但被认为具有低全身毒性。Dimethyl sulfoxide 还表现出防冻和抑菌的特性。
MCE 提供符合《中国药典》 四部（2020年版）检验标准 (Ch.P) 的 Dimethyl sulfoxide。

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Dimethyl sulfoxide, meets analytical specification of Ch.P. Chemical Structure

Dimethyl sulfoxide, meets analytical specification of Ch.P. Chemical Structure

CAS No. : 67-68-5

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规格 价格 是否有货 数量
10 mL ￥100
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100 mL ￥350
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200 mL ￥520
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500 mL ￥850
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Other Forms of Dimethyl sulfoxide, meets analytical specification of Ch.P.:

Dimethyl sulfoxide, meets analytical specification of Ch.P. 相关抗体

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  • 生物活性

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生物活性

Dimethyl sulfoxide (DMSO) is an aprotic solvent that dissolves polar and non-polar compounds, including water-insoluble therapeutic and toxic agents. Dimethyl sulfoxide (DMSO) has a strong affinity for water and can rapidly penetrate or enhance the penetration of other substances into biological membranes. Dimethyl sulfoxide also has potential free radical scavenging and anticholinesterase effects and may affect coagulation activity. Dimethyl sulfoxide also induces histamine release from mast cells but is thought to have low systemic toxicity. Dimethyl sulfoxide also exhibits antifreeze and antibacterial properties[1][2][3].
MCE provides Dimethyl sulfoxide that complies with the inspection standards (Ch.P) of Part 4 of the Chinese Pharmacopoeia (2020 Edition).

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HEK293 IC50
232 μM
Compound: DMSO
Antiproliferative activity against HEK293 cells after 48 hrs by MTT assay
Antiproliferative activity against HEK293 cells after 48 hrs by MTT assay
[PMID: 27108400]
HL-60 IC50
108 μM
Compound: DMSO
Antiproliferative activity against human HL60 cells after 48 hrs by MTT assay
Antiproliferative activity against human HL60 cells after 48 hrs by MTT assay
[PMID: 27108400]
LN-18 IC50
223 μM
Compound: DMSO
Antiproliferative activity against human LN18 cells after 48 hrs by MTT assay
Antiproliferative activity against human LN18 cells after 48 hrs by MTT assay
[PMID: 27108400]
MDCK-II GI50
123 μM
Compound: DMSO
Growth inhibition of MDCK2 cells after 72 hrs by MTT assay
Growth inhibition of MDCK2 cells after 72 hrs by MTT assay
[PMID: 32787102]
MDCK-II GI50
137 μM
Compound: DMSO
Growth inhibition of MDCK2 cells over expressing human ABCG2 after 72 hrs by MTT assay
Growth inhibition of MDCK2 cells over expressing human ABCG2 after 72 hrs by MTT assay
[PMID: 32787102]
THP-1 IC50
119 μM
Compound: DMSO
Antiproliferative activity against human THP1 cells after 48 hrs by MTT assay
Antiproliferative activity against human THP1 cells after 48 hrs by MTT assay
[PMID: 27108400]
体外研究
(In Vitro)

DMSO 是一种有机溶剂，可与水、脂类和有机试剂自由混溶。这些特性允许出色的膜渗透。DMSO 的作用机制被认为是抗炎作用、神经阻断作用、平滑肌松弛作用和胶原抑制作用的综合作用[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Dimethyl sulfoxide, meets analytical specification of Ch.P. 相关抗体:
Clinical Trial
分子量

78.13

Formula

C2H6OS
CAS 号
性状

<18.4°C 固体,>18.4°C 液体

颜色

Colorless to off-white

中文名称

二甲基亚砜, meets analytical specification of Ch.P.
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Store at room temperature 3 years
纯度 & 产品资料

纯度: 100.0%

COA (272 KB)

产品使用指南 (1538 KB)
参考文献

Dimethyl sulfoxide, meets analytical specification of Ch.P. 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

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