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  6. Breviscapine

Breviscapine  (Synonyms: Breviscapinun)

目录号: HY-107802 纯度: 95.59%
COA 产品使用指南

摩尔计算器

Breviscapine 是灯盏花的黄酮类粗提取物，85% 以上为有效成分，灯盏花乙素。Breviscapine 具有广泛的心血管药理活性，如增加血流量、改善微循环、扩张血管、降低血液粘度、促进纤溶、抑制血小板聚集、血栓形成等。Breviscapine 已用于脑梗塞及其后遗症、脑血栓、冠心病、心绞痛的研究中发挥出优良效力。

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Breviscapine Chemical Structure

Breviscapine Chemical Structure

CAS No. : 116122-36-2

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Customer Review

Breviscapine 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Breviscapine is a crude flavonoid extract of Breviscapine, which is more than 85% of the active ingredient, Breviscapine. Breviscapine has a wide range of cardiovascular pharmacological activities, such as increasing blood flow, improving microcirculation, dilating blood vessels, reducing blood viscosity, promoting fibrinolysis, inhibiting platelet aggregation and thrombosis. Breviscapine has been used in the study of cerebral infarction and its sequelae, cerebral thrombosis, coronary heart disease and angina pectoris[1][2].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A549 IC50
> 50 μM
Compound: 1
Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
Antiproliferative activity against human A549 cells after 72 hrs by MTT assay
[PMID: 30243153]
Bel-7402 IC50
> 50 μM
Compound: 1
Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay
Antiproliferative activity against human Bel7402 cells after 72 hrs by MTT assay
[PMID: 30243153]
HCT-116 IC50
77 μM
Compound: Scutellarin
Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
Antiproliferative activity against human HCT116 cells after 72 hrs by MTT assay
[PMID: 28458133]
HepG2 IC50
56.09 μM
Compound: Scutellarin
Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay
Antiproliferative activity against human HepG2 cells after 72 hrs by MTT assay
[PMID: 28458133]
L02 IC50
> 100 μM
Compound: Scutellarin
Antiproliferative activity against human LO2 cells after 72 hrs by MTT assay
Antiproliferative activity against human LO2 cells after 72 hrs by MTT assay
[PMID: 28458133]
L02 IC50
> 50 μM
Compound: 1
Cytotoxicity against human LO2 cells assessed as decrease in cell viability after 72 hrs by MTT assay
Cytotoxicity against human LO2 cells assessed as decrease in cell viability after 72 hrs by MTT assay
[PMID: 30243153]
MCF7 IC50
> 100 μM
Compound: Scutellarin
Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
[PMID: 28458133]
MCF7 IC50
> 50 μM
Compound: 1
Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 72 hrs by MTT assay
[PMID: 30243153]
PC-3 IC50
72.9 μM
Compound: Scutellarin
Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay
Antiproliferative activity against human PC3 cells after 72 hrs by MTT assay
[PMID: 28458133]
分子量

1293.34

Formula

C54H84N16O21
CAS 号
性状

固体

颜色

Light yellow to yellow

中文名称

灯盏花素
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

溶解性数据
细胞实验： 

DMSO 中的溶解度 : 100 mg/mL (77.32 mM; 超声助溶 (<60°C); 吸湿的 DMSO 对产品的溶解度有显著影响，请使用新开封的 DMSO)

H2O 中的溶解度 : < 0.1 mg/mL (insoluble)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 0.7732 mL 3.8660 mL 7.7319 mL
5 mM 0.1546 mL 0.7732 mL 1.5464 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料
参考文献

Breviscapine 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month (protect from light)。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.7732 mL 3.8660 mL 7.7319 mL 19.3298 mL
5 mM 0.1546 mL 0.7732 mL 1.5464 mL 3.8660 mL
10 mM 0.0773 mL 0.3866 mL 0.7732 mL 1.9330 mL
15 mM 0.0515 mL 0.2577 mL 0.5155 mL 1.2887 mL
20 mM 0.0387 mL 0.1933 mL 0.3866 mL 0.9665 mL
25 mM 0.0309 mL 0.1546 mL 0.3093 mL 0.7732 mL
30 mM 0.0258 mL 0.1289 mL 0.2577 mL 0.6443 mL
40 mM 0.0193 mL 0.0966 mL 0.1933 mL 0.4832 mL
50 mM 0.0155 mL 0.0773 mL 0.1546 mL 0.3866 mL
60 mM 0.0129 mL 0.0644 mL 0.1289 mL 0.3222 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Breviscapine116122-36-2Breviscapinun灯盏花素OthersInhibitorinhibitorinhibit

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