Adk - adenosine kinase Gene

中文名称：腺苷激酶

种属: Mus musculus

同用名: Ak; 2310026J05Rik; 5033405D03Rik

关于 Adk

功能概要

该基因编码的蛋白可启动腺苷激酶活性和脱氧腺苷激酶活性。参与AMP打捞； GMP补救；和潮湿的打捞。在 dATP 生物合成过程和嘌呤核糖核苷回收过程的上游或内部起作用。位于细胞质和细胞核中。以多种结构表达，包括消化系统；脑;泌尿生殖系统；感觉器官；和骨架。用于研究脂肪肝疾病。该基因的人类直系同源物与由于腺苷激酶缺乏引起的高甲硫氨酸血症有关。与人 ADK（腺苷激酶）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables Adenosine Kinase activity and deoxyadenosine kinase activity. Involved in AMP salvage; GMP salvage; and dAMP salvage. Acts upstream of or within dATP biosynthetic process and purine ribonucleoside salvage. Located in cytosol and nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; sensory organ; and skeleton. Used to study fatty liver disease. Human ortholog(s) of this gene implicated in hypermethioninemia due to Adenosine Kinase deficiency. Orthologous to human ADK (Adenosine Kinase). [provided by Alliance of Genome Resources, Apr 2022]