1. Gene
  2. Cxcr3 - chemokine (C-X-C motif) receptor 3 Gene

Cxcr3 - chemokine (C-X-C motif) receptor 3 Gene

中文名称:趋化因子 (CXC 基序) 受体 3

种属: Mus musculus

同用名: Cd183; Cmkar3

基因 ID: 12766 | 基因类型: protein coding

关于 Cxcr3

Chromosome X: 100,775,141-100,777,875 reverse strand.GRCm39:CM001013.3

This gene has 1 transcript (splice variant), 289 orthologues, 25 paralogues and is associated with 17 phenotypes. Biased expression in spleen adult (RPKM 18.9), mammary gland adult (RPKM 1.3) and 11 other tissues.

功能概要

该基因编码一种跨膜蛋白,作为 CXR 趋化因子的受体发挥作用。通过这种蛋白质发出的信号调节多种生物过程,包括炎症、免疫和伤口愈合。这种蛋白质还在肿瘤生长和转移中发挥作用。 [RefSeq 提供,2015 年 5 月]

This gene encodes a transmembrane protein that functions as a receptor for C-X-R chemokines. Signalling through this protein regulates a variety of biological processes, including inflammation, immunity, and would healing. This protein also plays a role in tumor growth and metastasis. [provided by RefSeq, May 2015]

Cxcr3 基因产物(1)

mRNA Protein Name
NM_009910.3 NP_034040.1 C-X-C chemokine receptor type 3
基因本体论
  • 细胞组分
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell surface IDA
IDA: 通过直接分析推断
23620790 MGI
located in external side of plasma membrane IDA
IDA: 通过直接分析推断
19008373 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

Cxcr3 蛋白结构

7tmA_CXCR3

7tmA_CXCR3: cd15180 (52 - 327)

7tmA_CXCR3

7tmA_CXCR3: cd15180 (52 - 79)

7tmA_CXCR3

7tmA_CXCR3: cd15180 (86 - 111)

7tmA_CXCR3

7tmA_CXCR3: cd15180 (122 - 152)

7tmA_CXCR3

7tmA_CXCR3: cd15180 (164 - 186)

7tmA_CXCR3

7tmA_CXCR3: cd15180 (210 - 239)

7tmA_CXCR3

7tmA_CXCR3: cd15180 (246 - 276)

7tmA_CXCR3

7tmA_CXCR3: cd15180 (295 - 320)

  • 0
  • 100
  • 200
  • 300
  • 367 a.a.
蛋白主名 其他名称

C-X-C chemokine receptor type 3

IP-10 receptor

interferon-inducible protein 10 receptor

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cxcr3 NCBI NCBI:2833