Gls - glutaminase Gene

中文名称：谷氨酰胺酶

种属: Mus musculus

同用名: 6330442B14; B230365M23Rik

关于 Gls

功能概要

该基因编码的蛋白可启动谷氨酰胺酶活性和相同的蛋白质结合活性。参与谷氨酸生物合成过程；谷氨酰胺分解代谢过程；和蛋白质同源四聚化。作用于化学突触传递的上游或内部；通过神经系统过程调节呼吸气体交换；和哺乳行为。预测位于线粒体中。以多种结构表达，包括消化系统；心血管系统;泌尿生殖系统；神经系统;和感觉器官。该基因的人类直向同源基因与发育和癫痫性脑病 71 相关。与人类 GLS（谷氨酰胺酶）直向同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables Glutaminase activity and identical protein binding activity. Involved in glutamate biosynthetic process; glutamine catabolic process; and protein homotetramerization. Acts upstream of or within chemical synaptic transmission; regulation of respiratory gaseous exchange by nervous system process; and suckling behavior. Predicted to be located in mitochondrion. Is expressed in several structures, including alimentary system; cardiovascular system; genitourinary system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 71. Orthologous to human GLS (Glutaminase). [provided by Alliance of Genome Resources, Apr 2022]