CDCA2 - cell division cycle associated 2 Gene

中文名称：细胞分裂周期相关 2

种属: Homo sapiens

同用名: PPP1R81; Repo-Man

关于 CDCA2

功能概要

该基因编码细胞周期相关蛋白、蛋白磷酸酶 1 的靶向亚基，在后期将该蛋白靶向染色质。这两种蛋白质包含一个磷酸酶复合物，该复合物参与核膜重建和 DNA 损伤反应的调节。编码的蛋白质也可能在癌症进展中发挥作用。可变剪接导致多个转录本变体。[RefSeq 提供，2015 年 12 月]

This gene encodes a targeting subunit of the cell-cycle associated protein, protein Phosphatase 1, with a role in targeting this protein to chromatin during anaphase. These two proteins comprise a Phosphatase complex that is involved in nuclear envelope reformation and regulation of the DNA damage response. The encoded protein may also play a role in Cancer progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]