1. Gene
  2. Acod1 - aconitate decarboxylase 1 Gene

Acod1 - aconitate decarboxylase 1 Gene

种属: Mus musculus

同用名: CAD; Irg1

基因 ID: 16365 | 基因类型: protein coding

关于 Acod1

功能概要

Enables aconitate decarboxylase activity. Involved in several processes, including cellular response to cytokine stimulus; negative regulation of defense response; and negative regulation of signal transduction. Acts upstream of or within response to lipopolysaccharide. Located in mitochondrion. Orthologous to human ACOD1 (aconitate decarboxylase 1). [provided by Alliance of Genome Resources, Apr 2022]

Acod1 基因产物(1)

mRNA Protein Name
NM_008392.1 NP_032418.1 cis-aconitate decarboxylase
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables aconitate decarboxylase activity IDA
IDA: 通过直接分析推断
23610393 MGI
enables aconitate decarboxylase activity IMP
IMP: 通过突变表型推断
30635240 MGI
enables protein homodimerization activity IDA
IDA: 通过直接分析推断
31548418 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to interferon-beta IDA
IDA: 通过直接分析推断
19014335 MGI
involved in cellular response to interleukin-1 IDA
IDA: 通过直接分析推断
19014335 MGI
involved in cellular response to lipopolysaccharide IDA
IDA: 通过直接分析推断
23609450 MGI
involved in cellular response to molecule of bacterial origin IDA
IDA: 通过直接分析推断
19014335 MGI
involved in cellular response to progesterone stimulus IDA
IDA: 通过直接分析推断
14500577 MGI
involved in cellular response to tumor necrosis factor IDA
IDA: 通过直接分析推断
19014335 MGI
involved in cellular response to type II interferon IDA
IDA: 通过直接分析推断
19014335 MGI
involved in defense response IDA
IDA: 通过直接分析推断
23610393 MGI
involved in defense response to virus IMP
IMP: 通过突变表型推断
30635240 MGI
involved in embryo implantation IMP
IMP: 通过突变表型推断
14500577 MGI
involved in negative regulation of NF-kappaB transcription factor activity IMP
IMP: 通过突变表型推断
23609450 MGI
involved in negative regulation of inflammatory response IDA
IDA: 通过直接分析推断
23609450 MGI
involved in negative regulation of innate immune response IDA
IDA: 通过直接分析推断
23609450 MGI
involved in negative regulation of toll-like receptor 2 signaling pathway IMP
IMP: 通过突变表型推断
23609450 MGI
involved in negative regulation of toll-like receptor 4 signaling pathway IDA
IDA: 通过直接分析推断
23609450 MGI
involved in negative regulation of type I interferon production IMP
IMP: 通过突变表型推断
23609450 MGI
involved in positive regulation of antimicrobial humoral response IDA
IDA: 通过直接分析推断
23610393 MGI
involved in positive regulation of reactive oxygen species metabolic process IDA
IDA: 通过直接分析推断
23609450 MGI
acts upstream of or within response to bacterium IEP
IEP: 通过表达模式推断
23012479 MGI
acts upstream of or within response to lipopolysaccharide IDA
IDA: 通过直接分析推断
7721348 MGI
involved in tolerance induction to lipopolysaccharide IDA
IDA: 通过直接分析推断
23609450 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrion IDA
IDA: 通过直接分析推断
19014335 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

cis-aconitate decarboxylase

cis-aconitic acid decarboxylase

immune-responsive gene 1 protein

immunoresponsive gene 1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Acod1 NCBI NCBI:730249