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  2. Ntsr2 - neurotensin receptor 2 Gene

Ntsr2 - neurotensin receptor 2 Gene

中文名称:神经降压素受体 2

种属: Mus musculus

同用名: NT2R; NTR2; NTRL; NT-R-2

基因 ID: 18217 | 基因类型: protein coding

关于 Ntsr2

Chromosome 12: 16,703,383-16,710,228 forward strand.GRCm39:CM001005.3

This gene has 5 transcripts (splice variants), 79 orthologues, 14 paralogues and is associated with 4 phenotypes. Biased expression in genital fat pad adult (RPKM 7.4), cortex adult (RPKM 64.8) and 5 other tissues.

功能概要

该基因编码的蛋白可启动 G 蛋白偶联神经降压素受体活性。作用于磷脂酶 C 激活 G 蛋白偶联受体信号通路的上游或内部,并调节膜电位。位于膜内。与人类 NTSR2(神经降压素受体 2)同源。 [由基因组资源联盟提供,2022 年 4 月]

Enables G protein-coupled Neurotensin Receptor activity. Acts upstream of or within Phospholipase C-activating G protein-coupled receptor signaling pathway and regulation of membrane potential. Located in membrane. Orthologous to human NTSR2 (Neurotensin Receptor 2). [provided by Alliance of Genome Resources, Apr 2022]

Ntsr2 基因产物(5)

mRNA Protein Name
NM_001361702.2 NP_001348631.1 neurotensin receptor type 2 isoform 2
NM_001361703.2 NP_001348632.1 neurotensin receptor type 2 isoform 3
NM_001412674.1 NP_001399603.1 neurotensin receptor type 2 isoform 4
NM_001412675.1 NP_001399604.1 neurotensin receptor type 2 isoform 5
NM_008747.3 NP_032773.2 neurotensin receptor type 2 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables G protein-coupled neurotensin receptor activity IDA
IDA: 通过直接分析推断
8795617 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within phospholipase C-activating G protein-coupled receptor signaling pathway IDA
IDA: 通过直接分析推断
8795617 MGI
acts upstream of or within regulation of membrane potential IDA
IDA: 通过直接分析推断
8795617 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in membrane IDA
IDA: 通过直接分析推断
8795617 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

Ntsr2 蛋白结构

7tm_GPCRs

7tm_GPCRs: cl28897 (32 - 368)

7tm_GPCRs

7tm_GPCRs: cd14964 (34 - 58)

7tm_GPCRs

7tm_GPCRs: cd14964 (68 - 90)

7tm_GPCRs

7tm_GPCRs: cd14964 (108 - 130)

7tm_GPCRs

7tm_GPCRs: cd14964 (153 - 169)

7tm_GPCRs

7tm_GPCRs: cd14964 (203 - 226)

7tm_GPCRs

7tm_GPCRs: cd14964 (295 - 317)

7tm_GPCRs

7tm_GPCRs: cd14964 (336 - 361)

  • 0
  • 100
  • 200
  • 300
  • 416 a.a.
蛋白主名 其他名称

neurotensin receptor type 2

low affinity neurotensin receptor

low-affinity levocabastine-sensitive neurotensin receptor

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Ntsr2 NCBI NCBI:23620