Rxrg - retinoid X receptor gamma Gene

中文名称：视黄醇 X 受体 γ

种属: Mus musculus

同用名: Nr2b3

关于 Rxrg

功能概要

该基因编码的蛋白可启动 RNA 聚合酶 II 转录调节区序列特异性 DNA 结合活性；相同的蛋白质结合活性；和核受体活性。在参与细胞对化学刺激和视黄酸受体信号通路的反应的 RNA 聚合酶 II 启动子转录的上游或正调控中起作用。预测位于核内。预计是 RNA 聚合酶 II 转录调节复合物的一部分。以多种结构表达，包括消化系统；中枢神经系统;泌尿生殖系统；肌肉组织；和感觉器官。该基因的人类直系同源物与肺非小细胞癌有关。与人类 RXRG（类视黄醇 X 受体γ）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; identical protein binding activity; and nuclear receptor activity. Acts upstream of or within positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus and retinoic acid receptor signaling pathway. Predicted to be located in nucleus. Predicted to be part of RNA polymerase II transcription regulator complex. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; musculature; and sensory organ. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Orthologous to human RXRG (retinoid X receptor gamma). [provided by Alliance of Genome Resources, Apr 2022]