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  3. Slc10a2 - solute carrier family 10, member 2 Gene

Slc10a2 - solute carrier family 10, member 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：溶质载体家族 10 ，成员 2

种属: Mus musculus

同用名: ASBT; IBAT; ISBT; 9130221J18Rik

基因 ID: 20494 | 基因类型: protein coding

关于 Slc10a2

Chromosome 8: 5,133,219-5,155,351 reverse strand.GRCm39:CM001001.3

This gene has 1 transcript (splice variant), 213 orthologues, 6 paralogues and is associated with 13 phenotypes. Biased expression in large intestine adult (RPKM 2.9), kidney adult (RPKM 7.5) and 2 other tissues.

功能概要

预计该基因编码的蛋白可启动胆汁酸：钠同向转运体活性。在对细菌的反应上游或反应内起作用。位于顶端质膜和微绒毛。在 Peyer's patch 中表达；泌尿生殖系统；和小肠。该基因的人类直系同源物与肠道疾病有关。与人类 SLC10A2（溶质载体家族 10 成员 2）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable bile acid:sodium symporter activity. Acts upstream of or within response to bacterium. Located in apical plasma membrane and microvillus. Is expressed in Peyer's patch; genitourinary system; and small intestine. Human ortholog(s) of this gene implicated in intestinal disease. Orthologous to human SLC10A2 (solute carrier family 10 member 2). [provided by Alliance of Genome Resources, Apr 2022]

Slc10a2 基因产物(1)

mRNA Protein Name
NM_011388.3 NP_035518.1 ileal sodium/bile acid cotransporter
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within response to bacterium IEP
IEP: 通过表达模式推断
23012479 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical plasma membrane IDA
IDA: 通过直接分析推断
23747249 MGI
located in microvillus IDA
IDA: 通过直接分析推断
23200860 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

Slc10a2 蛋白结构

bass

bass: TIGR00841 (28 - 313)

  • 0
  • 100
  • 200
  • 300
  • 348 a.a.
蛋白主名 其他名称

ileal sodium/bile acid cotransporter

Na(+)-dependent ileal bile acid transporter

apical sodium-dependent bile acid transporter

ileal Na(+)/bile acid cotransporter

ileal sodium-dependent bile acid transporter

sodium/taurocholate cotransporting polypeptide, ileal

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-168523 S1647 Inhibitor / 否
HY-RS12986 SLC10A2 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS12987 Slc10a2 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS12988 Slc10a2 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Slc10a2 NCBI NCBI:6555
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