2. Gene
  3. Tacr3 - tachykinin receptor 3 Gene

Tacr3 - tachykinin receptor 3 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：速激肽受体 3

种属: Rattus norvegicus

同用名: Nkr; Nmkr; Tac3r

基因 ID: 24808 | 基因类型: protein coding

关于 Tacr3

Primary_assembly 2: 223,266,536-223,363,791 forward strand.mRatBN7.2:CM026975.1

This gene has 1 transcript (splice variant), 258 orthologues, 50 paralogues and is associated with 14 phenotypes. Biased expression in Brain (RPKM 3.9), Kidney (RPKM 7.7) and 4 other tissues.

功能概要

该基因编码的蛋白可启动速激肽受体活性。参与多个过程，包括高渗盐度反应；子宫平滑肌收缩的正调节；和对生物碱的反应。位于几种细胞成分中，包括树突膜；神经细胞体膜；和核。用于研究高血压。视觉癫痫的生物标志物。该基因的人类直系同源物与低促性腺激素性性腺功能减退症 11 相关，伴有或不伴有嗅觉缺失。与人 TACR3（速激肽受体 3）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables tachykinin receptor activity. Involved in several processes, including hyperosmotic salinity response; positive regulation of uterine smooth muscle contraction; and response to alkaloid. Located in several cellular components, including dendrite membrane; neuronal cell body membrane; and nucleus. Used to study hypertension. Biomarker of visual epilepsy. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 11 with or without anosmia. Orthologous to human TACR3 (tachykinin receptor 3). [provided by Alliance of Genome Resources, Apr 2022]

Tacr3 基因产物(1)

mRNA Protein Name
NM_017053.1 NP_058749.1 neuromedin-K receptor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables tachykinin receptor activity IDA
IDA: 通过直接分析推断
1662278 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of blood pressure IDA
IDA: 通过直接分析推断
2478257 RGD
involved in positive regulation of heart rate IDA
IDA: 通过直接分析推断
2471579 RGD
involved in positive regulation of uterine smooth muscle contraction IDA
IDA: 通过直接分析推断
12390879 RGD
involved in regulation of dopamine metabolic process IDA
IDA: 通过直接分析推断
8574643 RGD
involved in regulation of feeding behavior IDA
IDA: 通过直接分析推断
2462199 RGD
involved in response to cocaine IMP
IMP: 通过突变表型推断
17445241 RGD
involved in response to estradiol IDA
IDA: 通过直接分析推断
12390879 RGD
involved in response to estradiol IEP
IEP: 通过表达模式推断
10342838 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in dendrite membrane IDA
IDA: 通过直接分析推断
16357093 RGD
located in neuronal cell body membrane IDA
IDA: 通过直接分析推断
16357093 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

Tacr3 蛋白结构

7tmA_NKR_NK3R

7tmA_NKR_NK3R: cd16003 (72 - 353)

7tmA_NKR_NK3R

7tmA_NKR_NK3R: cd16003 (73 - 99)

7tmA_NKR_NK3R

7tmA_NKR_NK3R: cd16003 (106 - 132)

7tmA_NKR_NK3R

7tmA_NKR_NK3R: cd16003 (144 - 174)

7tmA_NKR_NK3R

7tmA_NKR_NK3R: cd16003 (185 - 206)

7tmA_NKR_NK3R

7tmA_NKR_NK3R: cd16003 (230 - 259)

7tmA_NKR_NK3R

7tmA_NKR_NK3R: cd16003 (278 - 308)

7tmA_NKR_NK3R

7tmA_NKR_NK3R: cd16003 (321 - 346)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 452 a.a.
蛋白主名 其他名称

neuromedin-K receptor

NK-3 receptor

NK-3R

Neuromedin K receptor (Neurokinin B/Tachikin 3)

neurokinin B receptor

tachikin receptor 3

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS14149 TACR3 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS14150 Tacr3 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS14151 Tacr3 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Tacr3 NCBI NCBI:6870
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