2. Gene
  3. IL36B - interleukin 36 beta Gene

IL36B - interleukin 36 beta Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：白细胞介素 36 β

种属: Homo sapiens

同用名: FIL1; FIL1H; IL1F8; IL1H2; IL-1F8; IL-1H2; IL1-ETA; FIL1-(ETA); FILI-(ETA)

基因 ID: 27177 | 基因类型: protein coding

关于 IL36B

Cytogenetic location: 2q14.1 Genomic coordinates (GRCh38): 2:113,022,089-113,052,867 (from NCBI)

This gene has 2 transcripts (splice variants), 218 orthologues and 7 paralogues. Biased expression in skin (RPKM 1.1) and esophagus (RPKM 0.5).

功能概要

该基因编码的蛋白质是白介素 1 细胞因子家族的成员。蛋白质结构建模表明，这种细胞因子可能包含一个 12 链 β-三叶结构，该结构在 IL1A (IL-A alpha) 和 IL1B (IL-1 beta) 之间是保守的。该基因和其他八个白细胞介素 1 家族基因在 2 号染色体上形成细胞因子基因簇。已报道了编码不同亚型的两种可变剪接的转录物变体。[RefSeq 提供，2008 年 7 月]

The protein encoded by this gene is a member of the interleukin 1 cytokine family. Protein structure modeling indicated that this cytokine may contain a 12-stranded beta-trefoil structure that is conserved between IL1A (IL-A alpha) and IL1B (IL-1 beta). This gene and eight Other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. Two alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

IL36B 基因产物(2)

mRNA Protein Name
NM_014438.5 NP_055253.2 interleukin-36 beta isoform 1
NM_173178.3 NP_775270.1 interleukin-36 beta isoform 2
蛋白主名 其他名称

interleukin-36 beta

FIL1 eta

重组 IL36B 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72545 IL-36 beta/IL-1F8 Protein, Human Q9NZH7-2 (R5-E157) ≥95%
HY-P74803 IL-36 beta/IL-1F8 Protein, Human (His) Q9NZH7-2 (K5-E157) ≥95%
HY-P74803AF Animal-Free IL-36 beta/IL-1F8 Protein, Human (His) Q9NZH7-2 (R5-E157) ≥95%

关联疾病

疾病名称 别名
Impetigo Herpetiformis
Psoriasis 14, Pustular

Generalized Pustular Psoriasis

Gpp

Ditra

Acrodermatitis Continua Of Hallopeau

Palmoplantar Pustulosis

PSORS14

Interleukin 36 Receptor Antagonist Deficiency

Psorp

Pustular Psoriasis 14

Deficiency Of Il-36r Antagonist

Acute Generalised Pustular Psoriasis

Deficiency Of The Interleukin-36 Receptor Antagonist

Generalized Pustular Psoriasis Of Von Zumbusch

Von Zumbusch Psoriasis

Deficiency Of Il-36ra

Psoriasis, Pustular, Generalized

Psoriasis, Pustular, Type 14

Pustulosis Of Palms And Soles

Acute Generalized Pustular Psoriasis

Palmoplantar Pustular Psoriasis

Pustulosis Palmaris Et Plantaris

Ppp - [Palmoplantar Pustulosis]

Pustular Psoriasis Of The Palms And Soles

Pustular Bacterid
Miliaria Crystallina
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06760 IL36B Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus IL36B VGNC VGNC:30157
Mus musculus IL36B MGD MGI:1916927
Macaca mulatta IL36B VGNC VGNC:73603
Rattus norvegicus IL36B RGD RGD:1307847
Canis familiaris IL36B VGNC VGNC:41984
Others IL36B NCBI
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z