1. Gene
  2. Mc2r - melanocortin 2 receptor Gene

Mc2r - melanocortin 2 receptor Gene

中文名称:黑皮质素 2 受体

种属: Rattus norvegicus

基因 ID: 282839 | 基因类型: protein coding

关于 Mc2r

Primary_assembly 18: 62,004,948-62,015,488 reverse strand.mRatBN7.2:CM026991.1

This gene has 1 transcript (splice variant), 178 orthologues, 18 paralogues and is associated with 10 phenotypes. Biased expression in Adrenal (RPKM 393.7) and Muscle (RPKM 25.).

功能概要

预计该基因编码的蛋白可启动 G 蛋白偶联受体活性。参与胎盘发育。位于细胞质和质膜中。中毒性休克综合征的生物标志物。该基因与 West 综合征和糖皮质激素缺乏症 1 相关的人类直向同源基因。与人类 MC2R(黑皮质素 2 受体)直向同源基因。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable G protein-coupled receptor activity. Involved in placenta development. Located in cytoplasm and plasma membrane. Biomarker of toxic shock syndrome. Human ortholog(s) of this gene implicated in West syndrome and glucocorticoid deficiency 1. Orthologous to human MC2R (melanocortin 2 receptor). [provided by Alliance of Genome Resources, Apr 2022]

Mc2r 基因产物(1)

mRNA Protein Name
NM_001100491.1 NP_001093961.1 adrenocorticotropic hormone receptor
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in placenta development IEP
IEP: 通过表达模式推断
15781985 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

Mc2r 蛋白结构

7tmA_MC2R_ACTH_R

7tmA_MC2R_ACTH_R: cd15350 (24 - 286)

7tmA_MC2R_ACTH_R

7tmA_MC2R_ACTH_R: cd15350 (25 - 51)

7tmA_MC2R_ACTH_R

7tmA_MC2R_ACTH_R: cd15350 (58 - 84)

7tmA_MC2R_ACTH_R

7tmA_MC2R_ACTH_R: cd15350 (102 - 132)

7tmA_MC2R_ACTH_R

7tmA_MC2R_ACTH_R: cd15350 (144 - 164)

7tmA_MC2R_ACTH_R

7tmA_MC2R_ACTH_R: cd15350 (169 - 198)

7tmA_MC2R_ACTH_R

7tmA_MC2R_ACTH_R: cd15350 (211 - 241)

7tmA_MC2R_ACTH_R

7tmA_MC2R_ACTH_R: cd15350 (254 - 279)

  • 0
  • 100
  • 200
  • 296 a.a.
蛋白主名 其他名称

adrenocorticotropic hormone receptor

melanocortin 2 receptor (adrenocorticotropic hormone)

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Mc2r NCBI NCBI:4158