1. Gene
  2. Map4k2 - mitogen activated protein kinase kinase kinase kinase 2 Gene

Map4k2 - mitogen activated protein kinase kinase kinase kinase 2 Gene

中文名称:有丝分裂原活化蛋白激酶激酶激酶 2

种属: Rattus norvegicus

基因 ID: 293694 | 基因类型: protein coding

关于 Map4k2

Primary_assembly 1: 203,645,153-203,660,331 forward strand.mRatBN7.2:CM026974.1

This gene has 1 transcript (splice variant), 101 orthologues, 36 paralogues and is associated with 5 phenotypes. Biased expression in Thymus (RPKM 158.7), Lung (RPKM 156.9) and 9 other tissues.

功能概要

预测该基因编码的蛋白可启动 ATP 绑定活动; MAP激酶激酶激酶活性;和有丝分裂原活化蛋白激酶激酶激酶结合活性。预计参与多个过程,包括 MAPK 级联的正调控;蛋白质磷酸化;和囊泡靶向。与人 MAP4K2(丝裂原活化蛋白激酶激酶 kinase kinase 2)同源。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable ATP binding activity; MAP kinase kinase kinase kinase activity; and mitogen-activated protein kinase kinase kinase binding activity. Predicted to be involved in several processes, including positive regulation of MAPK cascade; protein phosphorylation; and vesicle targeting. Orthologous to human MAP4K2 (mitogen-activated protein kinase kinase kinase kinase 2). [provided by Alliance of Genome Resources, Apr 2022]

Map4k2 基因产物(1)

mRNA Protein Name
NM_001106329.1 NP_001099799.1 mitogen-activated protein kinase kinase kinase kinase 2

Map4k2 蛋白结构

STKc_MAP4K3_like

STKc_MAP4K3_like: cd06613 (15 - 271)

CNH

CNH: smart00036 (488 - 800)

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  • 821 a.a.
蛋白主名 其他名称

mitogen-activated protein kinase kinase kinase kinase 2

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Map4k2 NCBI NCBI:5871