2. Gene
  3. Slc10a2 - solute carrier family 10 member 2 Gene

Slc10a2 - solute carrier family 10 member 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：溶质载体家族 10 成员 2

种属: Rattus norvegicus

同用名: ASBT; IBAT; ISBT; ISBAT

基因 ID: 29500 | 基因类型: protein coding

关于 Slc10a2

Primary_assembly 16: 84,374,862-84,409,475 forward strand.mRatBN7.2:CM026989.1

This gene has 2 transcripts (splice variants), 212 orthologues, 6 paralogues and is associated with 8 phenotypes. Biased expression in Kidney (RPKM 2.9), Testes (RPKM 1.9) and 1 other tissue.

功能概要

该基因编码的蛋白可启动胆汁酸：钠同向转运体活性。参与胆汁酸和胆汁盐的转运。位于顶端质膜和细胞核。蛋白酶体复合物的一部分。该基因的人类直系同源物与肠道疾病有关。与人类 SLC10A2（溶质载体家族 10 成员 2）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables bile acid:sodium symporter activity. Involved in bile acid and bile salt transport. Located in apical plasma membrane and nucleus. Part of Proteasome complex. Human ortholog(s) of this gene implicated in intestinal disease. Orthologous to human SLC10A2 (solute carrier family 10 member 2). [provided by Alliance of Genome Resources, Apr 2022]

Slc10a2 基因产物(1)

mRNA Protein Name
NM_017222.2 NP_058918.1 ileal sodium/bile acid cotransporter
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables bile acid:sodium symporter activity IDA
IDA: 通过直接分析推断
8770054 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in bile acid and bile salt transport IDA
IDA: 通过直接分析推断
8770054 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in apical plasma membrane IDA
IDA: 通过直接分析推断
8770054 RGD
part of proteasome complex IDA
IDA: 通过直接分析推断
15304498 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

Slc10a2 蛋白结构

bass

bass: TIGR00841 (28 - 314)

  • 0
  • 100
  • 200
  • 300
  • 348 a.a.
蛋白主名 其他名称

ileal sodium/bile acid cotransporter

Na(+)-dependent ileal bile acid transporter

apical sodium-dependent bile acid transporter

ileal Na(+)/bile acid cotransporter

ileal sodium-dependent bile acid transporter

sodium/taurocholate-cotransporting polypeptide, ileal

solute carrier family 10 (sodium/bile acid cotransporter family), member 2

solute carrier family 10 (sodium/bile acid cotransporter), member 2

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-168523 S1647 Inhibitor / 否
HY-RS12986 SLC10A2 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS12987 Slc10a2 Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS12988 Slc10a2 Rat Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Slc10a2 NCBI NCBI:6555
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